Results 141 to 150 of about 1,113,900 (284)

Depot‐Specific Insulin Receptor Isoform Dynamics During Human Adipose‐Derived Stem Cell Adipogenesis

Obesity, EarlyView.
Absolute quantification reveals depot‐specific insulin receptor (IR) isoform signatures in human adipose stem cells, with subcutaneous cells enriched in IRa and exhibiting greater adipogenic capacity and insulin responsiveness. The emergence of IR‐negative adipocytes highlights partially receptor‐independent pathways regulating human adipogenesis ...
Valentina Annamaria Genchi, Celeste Lauriola, Cristina Caccioppoli, Rossella D'Oria, Nicola Marrano, Giuseppina Biondi, Sebastio Perrini, Annalisa Natalicchio, Luigi Laviola, Francesco Giorgino, Angelo Cignarelli   +10 more
wiley   +1 more source

Globalizing Comparative Public Administration With Integrative Contextualization: State Autonomy in the Developmental Path of Hong Kong and Singapore

Public Administration and Development, EarlyView.
ABSTRACT The lack of a common variable for comparison has been a major obstacle to the development of Comparative Public Administration (CPA). State autonomy enables an integrative contextualization approach, allowing both the analysis of contextual individual country experiences and the generation of generalized comparable knowledge.
Wilson Wong
wiley   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

PROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima, Wilson Dias Segura, Leonardo Brogliato de Moraes, Reinaldo Souza Oliveira, Pedro Henrique Corteletti Manfio, Alison Felipe Alencar Chaves, Wagner Luiz Batista   +6 more
wiley   +1 more source

Deformation, Creep, and Dynamics in Glassy Ionomers

Journal of Polymer Science, EarlyView.
Ionic architecture tunes the inelastic deformation of glassy ionomers. Simulations show that ionic associations leave the small‐strain elastic baseline nearly unchanged, but strongly reinforce yielding, strain hardening, and creep resistance. Polyampholyte architectures suppress nonaffine mobility and stress‐induced fluidization most effectively by ...
Nazanin Sadeghi, Fardin Khabaz
wiley   +1 more source

Mortality in an invasive ant does not scale linearly with fipronil exposure

Pest Management Science, EarlyView.
Increasing fipronil concentration did not linearly increase yellow crazy ant mortality when introduced via horizontal transfer; high doses may limit food sharing. Queen mortality was low, and surviving workers were averse to feeding. Abstract Background Controlling eusocial invasive and other pestiferous insects is difficult.
Peter Yeeles, Angela Strain, Lori Lach
wiley   +1 more source

MADS-box out of the black box [PDF]

Molecular Ecology, 2010
openaire   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Porous Modified Calcium Carbonate as an Efficient Carrier for Gallic and Ascorbic Acids in Humidity‐Activated Oxygen Scavenging Systems

Packaging Technology and Science, EarlyView.
Porous modified calcium carbonate (MCC) is presented as an efficient carrier for humidity‐activated oxygen scavengers based on gallic acid and ascorbic acid. The porous MCC structure preserves high accessibility of the active compounds, enabling effective oxygen scavenging under high relative humidity, with performance governed by loading level ...
Nastasia M. Coray, Bettina Röcker, Gabriel Mäder, Fabien W. Monnard, Matthias Welker, Joachim Schoelkopf, Selcuk Yildirim   +6 more
wiley   +1 more source

Retrospective image analysis for long‐term demography using Google Earth imagery

Remote Sensing in Ecology and Conservation, EarlyView.
We demonstrate that high‐resolution Google Earth imagery, combined with minimal field validation, enables retrospective tracking of individual invasive plants. The image shows one of the monitored individuals of Opuntia sp. in Greece. Our approach reveals long‐term demographic patterns, recruitment dynamics, and spatial expansion without continuous ...
Erola Fenollosa, Garrett Cohen, Roberto Salguero‐Gómez   +2 more
wiley   +1 more source

Investigating the Environmental Impact of Additive Construction: A Systematic Analysis of the Life Cycle Assessment Studies

Sustainable Development, EarlyView.
ABSTRACT Additive Manufacturing (AM) has been identified as a potential catalyst for a paradigm shift within the construction industry, due to its capacity to enhance sustainability, reduce waste, and augment design flexibility. This study presents a systematic literature review (SLR) that explores the application of Life Cycle Assessment (LCA) in ...
Antonio Mastropasqua, Francesco Paolo Lagrasta, Michele De Nicolò, Pierpaolo Pontrandolfo   +3 more
wiley   +1 more source