Results 111 to 120 of about 11,780 (226)
One‐step protocol enabling direct differentiation of human iPSCs into functional astrocytes within 5 weeks. Validated in > 60 lines across 10 labs. iPSC‐astrocytes support robust neuronal network development in co‐culture. ABSTRACT Astrocytes play a pivotal role in neuronal network development.
Imke M. E. Schuurmans +39 more
wiley +1 more source
The C117D oxidation mimic reveals the monomeric structure of SARS‐CoV‐2 main protease
Abstract The SARS‐CoV‐2 main protease (Mpro) is essential for viral replication and functions as a homodimer, with dimerization being critical for catalytic activity. Mpro contains an unusually high number of cysteine residues. Among these, C117 and the catalytic nucleophile C145 can form a reversible disulfide bond under oxidative conditions.
Sam Andress +2 more
wiley +1 more source
Expression Characterization of ABCDE Class MADS-Box Genes in Brassica rapa with Different Pistil Types. [PDF]
Zhang Y +12 more
europepmc +1 more source
Molecular insights and translational opportunities to enhance heat tolerance in rice
Abstract Heat stress is an increasingly serious threat to rice (Oryza sativa L.) productivity, yet the genetic and regulatory architecture underlying thermotolerance remain poorly resolved and fragmented across studies. Earlier research focused on individual pathways or specific developmental stages; however, recent advances now support an integrated ...
Prabhat Rana +7 more
wiley +1 more source
Multi‐Modal AI Approach in Depression Detection and Treatment: A Systematic Review of Last Decade
Overview of multimodal approaches for depression detection and treatment. ABSTRACT Depression is a common and devastating mental health illness with serious personal and societal consequences. Despite advancing treatment techniques, there are still hurdles in the effective diagnosis and treatment of depression, such as prompt diagnosis, personalized ...
Smith K. Khare +3 more
wiley +1 more source
Words matter: The prevalence and impact of negative emotive language in the equine industry
Summary Background Evidence from both human and veterinary medicine suggests a link between how patients are described and how they are treated, but the prevalence and consequences of negative emotive language (NEL) in the equine industry have received no systematic attention.
S. A. Catherall‐Ostler +3 more
wiley +1 more source
Autophagy in MASLD: A Metabolic and Precision Medicine Perspective
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga +4 more
wiley +1 more source
Proposed regulatory model for the axillary bud (AXB) fate determination of outgrowth into stolon and branch crown (BC) in strawberry. Summary In strawberry, the axillary bud (AXB) can produce either an elongated stem called stolon giving a daughter‐plant (asexual reproduction) or an inflorescence‐bearing branch crown (BC; sexual reproduction).
Marie Alonso +9 more
wiley +1 more source
Identification and expression analysis of the MADS-box genes of Kentucky bluegrass during inflorescence development. [PDF]
Zhang J, Ma H.
europepmc +1 more source
RGF signaling bridges root development and nonlethal thermal stress adaptation
Nonlethal high temperature inhibits root growth. Summary Roots adapt to growth‐restricting but nonlethal high temperatures. Although lethal heat shock and moderately elevated temperatures have been extensively studied, the effects of nonlethal thermal stress on root development remain unclear.
Yu‐Chun Hsiao +3 more
wiley +1 more source

