Results 111 to 120 of about 32,559 (283)

Screening for brain‐related comorbidities in Duchenne muscular dystrophy: Construction, reliability, and validity of the BIND screener

Developmental Medicine &Child Neurology, EarlyView.
The Brain Involvement iN Dystrophinopathies (BIND) screener is an 18‐item questionnaire with strong reliability and validity for identifying potential brain‐related comorbidities in Duchenne muscular dystrophy. It allows rapid, cross‐age and cross‐country screening for both clinical and research purposes, demonstrating good sensitivity and specificity.
Ruben Miranda, Pien M. M. Weerkamp, Anna Kolesnik, Chloe Geagan, Daniela Chieffo, Mariana Suárez‐Bagnasco, David Skuse, Elizabeth Vroom, Erik H. Niks, John Vissing, Isabelle Desguerre, Volker Straub, Francesco Muntoni, Eugenio Mercuri, Jos G. M. Hendriksen, on behalf of BIND Consortium, Nathalie Angeard, Dimitrios Athanasiou, Suzie‐Ann Bakker, Nathalie Boddaert, Ellie Drummond, Chloe Durrlemann, Fernanda Fortunato, Luis Miguel García‐Moreno, Mattia Gervasi, Rosanne Govaart, Irina Guliaeva, Catherine Hankinson, Leslie Hemar, Rebecca Hendel, Hermien Kan, Leevi Kerkela, Gregory Landon, Monika Malinova, William Mandy, Federica Moriconi, Monia Pellizzari, Sarah Poncet, Elvina Sakellariou, Sergiu Siminiuc, Anna Würgler Slipsager, Lily Smythe, Pietro Spitali, Mads Peter Godtfeldt Stemmerik, Asmus Vogel, Jeanne Wolstencroft, Camilla Zanetti   +46 more
wiley   +1 more source

MADS-box gene expression patterns correlate with drought and salt stress responses in Kentucky bluegrass (Poa pratensis L.) [PDF]

PeerJ
Background Kentucky bluegrass (Poa pratensis L.) is a perennial cool-season turfgrass commonly utilized in lawns. However, turfgrass quality is affected by abiotic stress.
Komal Tariq, Xue You, Yifeng Jin, Haoran Yu, Sabir Iqbal, Adil Hussain, Yang Chen   +6 more
doaj   +2 more sources

Plant Domestication Affects the Oviposition Behavior and Performance of Ganaspis kimorum, a Parasitoid of Drosophila suzukii

Entomologia Experimentalis et Applicata, EarlyView.
In this study, we investigated the effects of blueberry domestication on the oviposition behavior and performance of Ganaspis kimorum, a parasitoid of Drosophila suzukii. Domestication of blueberries reduced the oviposition‐searching behavior of the parasitoid but enhanced parasitoid performance, including offspring performance. Additionally, blueberry
Yahel Ben‐Zvi, Cesar Rodriguez‐Saona
wiley   +1 more source

Words matter: The prevalence and impact of negative emotive language in the equine industry

Equine Veterinary Education, EarlyView.
Summary Background Evidence from both human and veterinary medicine suggests a link between how patients are described and how they are treated, but the prevalence and consequences of negative emotive language (NEL) in the equine industry have received no systematic attention.
S. A. Catherall‐Ostler, A. M. Catherall‐Ostler, G. Pearson, A. R. Hollis   +3 more
wiley   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

The FEBS Journal, EarlyView.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior, Maria Anastasia Doumani, Hao Fu, Jelle van den Bor, Olof Idevall‐Hagren, Aristidis Moustakas   +5 more
wiley   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

The FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti, Gaia Galluzzi, Mario Frezzini, Cécile Exertier, Vittorio Brufani, Gianni Colotti, Giancarlo Ruocco, Jessica Rosati, Angelo Luigi Vescovi, Daniele Narzi, Ilaria Genovese, Andrea Ilari   +11 more
wiley   +1 more source

Thermal Thresholds and Genetic Sensitivity in Barrel Racing Performance of Quarter Horses Across Temperature–Humidity Indices

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Heat stress is an increasingly important challenge for the performance and welfare of equine athletes, particularly in competitions conducted across diverse climatic conditions. Understanding the genetic basis of performance responses to increasing thermal load is therefore essential to support robust genetic evaluation and sustainable ...
Mário Luiz Santana, Annaiza Braga Bignardi   +1 more
wiley   +1 more source

Intragenic Control of Expression of a Rice MADS Box Gene OsMADS1

Molecules and Cells, 2008
OsMADS1 is a rice MADS box gene necessary for floral development. To identify the key cis-regulatory regions for its expression, we utilized transgenic rice plants expressing GUS fusion constructs. Histochemical analysis revealed that the 5.7-kb OsMADS1 intragenic sequences, encompassing exon 1, intron 1, and a part of exon 2, together with the 1.9-kb ...
Jeon, JS, Lee, S, An, G
openaire   +2 more sources

Isolation and characterization of new MIKC*-type MADS-box genes from the moss Physcomitrella patens

, 2005
MADS-box genes encode for a large family of transcription-regulating proteins, which were isolated from all groups of eukaryotic organisms. The plant-specific MIKC-type MADS-box genes have been intensively analyzed for their roles in controlling ...
Saedler, H., W. Faigl, Verelst, W., Quodt, V., Riese, M., Faigl, W, M. Riese, Verelst, Wim, W. Verelst, Münster, T., Matthes, A., H. Saedler, Riese, M, T. Münster, Matthes, A, V. Quodt, A. Matthes, Saedler, H, Münster, Thomas, Faigl, W., Quodt, V   +20 more
core   +1 more source

Decoding stress resilience in soybean: Regulatory networks and precision breeding under climate change

Journal of Integrative Plant Biology, EarlyView.
This review covers recent progress in the understanding of stress‐responsive regulatory networks in soybean and highlights emerging genomic and breeding strategies. Integrating molecular insights and precision breeding will help to accelerate the development of climate‐resilient soybean cultivars.
Ali Shahzad, Monan Sun, Shuangkang Pei, Xiaoyu Liu, Yinhe Zhang, Keheng Xu, Hongtao Gao, Yonggang Zhou, Haiyan Li   +8 more
wiley   +1 more source