Results 141 to 150 of about 11,780 (226)

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy   +8 more
wiley   +1 more source

Red‐to‐Near‐Infrared Fluorescence Resonance Energy Transfer Reporters for Dual Imaging Applications

open access: yesSmall Methods, Volume 10, Issue 15, 7 August 2026.
Genetically encoded FRET biosensors reveal dynamic signaling in living cells, but overlapping spectra have limited the simultaneous monitoring of multiple pathways. We introduce a red‐to‐near infrared FRET pair, mRuby2/miRFP670nano3, compatible with existing reporters and enabling dual FLIM‐FRET without bleed‐through.
Van Thi‐Hong Tran   +5 more
wiley   +1 more source

Long‐term changes in functional diversity and its implications for mammalian conservation and ecological restoration in a grassland ecosystem

open access: yesFunctional Ecology, Volume 40, Issue 8, Page 2379-2391, August 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Paleontological data provide information on natural environments prior to human influence, which are useful for tracking changes in ecosystem functioning through time. During the Late Pleistocene, about 10% of terrestrial mammalian species were extinct in South America.
Thayara S. Carrasco   +3 more
wiley   +1 more source

Expression and Functional Analyses of Nymphaea caerulea MADS-Box Genes Contribute to Clarify the Complex Flower Patterning of Water Lilies. [PDF]

open access: yesFront Plant Sci, 2021
Moschin S   +8 more
europepmc   +1 more source

How Do Parents With Bipolar Disorder Perceive the Risk to the Next Generation? Results From a Qualitative Study

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Objectives There are several high‐risk studies of children of parents with bipolar disorder (BD); however, the impact of being an “At‐Risk” parent has seldom been studied. The aim is to explore how parents with BD perceive their potential heredity and how they feel toward their children being invited to take part in high‐risk family studies ...
Michelle Laigaard   +4 more
wiley   +1 more source

Targeting the noncatalytic activity of GSK3β modulates neuronal excitability in medium spiny neurons via Nav1.6 interactions

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 15, Page 4344-4363, August 2026.
Abstract Background and Purpose Kinases phosphorylate ion channels, but their noncatalytic roles via protein–protein interactions (PPI) are less understood. Here, we identified the peptidomimetic ZL141 to characterize the PPI between GSK3β and Nav1.6, revealing a noncatalytic role for GSK3β in regulating Nav1.6 currents and neuronal excitability ...
Aditya K. Singh   +19 more
wiley   +1 more source

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