Results 161 to 170 of about 118,614 (242)

The Role of N6‐Methyladenosine Modification in Health and Disease

MedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li, Yuanhai Sun, Wanfang Zheng, Lingqin Li, Yaqian Feng, Minyou Qi, Hanbing Li   +6 more
wiley   +1 more source

Comprehensive characterization of the <i>PeMADS</i> gene family in <i>Phyllostachys edulis</i> reveals new insights into floral development and evolution. [PDF]

Front Plant Sci
Zhu Y, Wang S, Shu D, Huang W, Ouyang Z, Zheng S, Hu C, Cao S, Sheng S.   +8 more
europepmc   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

MedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang, Jingfei Shi, Linlin Xu, Guangrui Zhao, Yue Chen, Lin Cheng, Xiaokang Li, Zhigang Sun, Shuhong Huang   +8 more
wiley   +1 more source

FLOWERING LOCUS T Genes MtFTb1 and MtFTb2 Act Redundantly to Promote Flowering Under Long Days in Medicago truncatula

Plant Direct, Volume 10, Issue 6, June 2026.
ABSTRACT Flowering time is a crucial agronomic trait affecting yield and plant performance in different climates and photoperiods. While the molecular pathways regulating photoperiodic flowering are well‐characterized in Arabidopsis and cereals, they remain poorly understood in many other groups of plants.
Soledad Perez Santangelo, Richard C. Macknight   +1 more
wiley   +1 more source

Limitations of the refolding pipeline for de novo protein design

Protein Science, Volume 35, Issue 6, June 2026.
Abstract With the emergence of powerful deep learning‐based tools, computational protein design has become a widely accessible technique. Nowadays, it is possible to perform both sequence and structure design in a matter of minutes, making the technology attractive to the broader scientific community. In protein design campaigns, one of the most common
Kerlen T. Korbeld, Vsevolod Viliuga, Maximilian J. L. J. Fürst   +2 more
wiley   +1 more source

Genome-Wide Analysis of the MADS-Box Gene Family and Expression Pattern Under Abiotic Stresses in <i>Lilium davidii</i> var. <i>unicolor</i>. [PDF]

Int J Mol Sci
Wang X, Zhu Y, Nie Y, Lan T, Zhang S, Zhao Y, Wang J, Ma C, He H.   +8 more
europepmc   +1 more source

Intrinsic conformational equilibria position arrestin‐2 for activation

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Arrestins regulate G protein‐coupled receptor (GPCR) signaling by undergoing large‐scale conformational rearrangements, yet the solution‐state equilibria that underlie arrestin pre‐activation remain poorly defined. While prior studies identified slow conformational exchange at the interdomain interface, these minor states could not be ...
Tucker J. Shriver, Kerem Kahraman, Mingzhe Pan, Çağdaş Dağ, Marco Tonelli, Scott A. Robson, Joshua J. Ziarek   +6 more
wiley   +1 more source

Transcriptional Regulation of Starch Biosynthesis in Sorghum Grain by a MIKC-Type MADS-Box Transcription Factor: An In Vitro Analysis. [PDF]

Plants (Basel)
Zhang J, Yan Z, Sun A, Gong X, Ma H, Huang M, Lin Y, Liu Z, Zheng L, Xiao Q.   +9 more
europepmc   +1 more source

Traversing the effects of ploidy changes in different Eragrostis curvula genotypes through high‐throughput RNA sequencing

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Polyploidization has played a key role in plant genome evolution. Eragrostis curvula (Schrad.) Ness, a perennial forage grass species of the Poaceae family, is an excellent model for investigating genome duplication due to its natural variation in ploidy levels.
D. F. Santoro, J. Carballo, M. C. Pasten, C. A. Gallo, E. Albertini, V. Echenique   +5 more
wiley   +1 more source

Characterization of multifunctional proteins from Helicobacter pylori

, 2010
This thesis reports the cloning, overexpression and characterization of two interesting proteins from Helicobacter pylori: Heat Shock protein A (HspA), and CoaX (Type III Pantothenate kinase).
Scannella, Alessandra
core