Results 151 to 160 of about 118,614 (242)

Gemcitabine activates the Hippo signaling pathway and suppresses tumor growth by stabilizing large tumor suppressor kinase 2 through the hypoxia‐inducible factor 1‐alpha/ubiquitin protein ligase E3 component N‐recognin 5 axis

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Abstract To investigate the molecular mechanism by which gemcitabine (GEM) inhibits ovarian cancer (OC) progression, focusing on the hypoxia‐inducible factor 1‐alpha (HIF1A)/UBR5/LATS2 axis and Hippo pathway. Bioinformatics analysis of gene expression omnibus datasets identified HIF1A‐associated modules.
Jin Zhang, Lixia Xu, Kai Guo, Weijia Dong, Xin Dai, Donghua Gu   +5 more
wiley   +1 more source

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

Chronic Diseases and Translational Medicine, Volume 12, Issue 2, Page 100-112, June 2026.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy, Cornelius J. Fernandez, Mohammad Hamid Nedai, Joseph M. Pappachan   +3 more
wiley   +1 more source

The Biology and Biochemistry of PhoH2 proteins

, 2013
PhoH2 proteins are found in a diverse range of organisms. To date little is known about these proteins and the role they play in the organisms in which they reside.
Andrews, Emma Sophie Vout
core  

Robust Constrained Partial Least Squares: A Robust Integrated Algorithm for Multivariate Regression in the Presence of Outliers, Interfering Analytes, and Structured External Influences

Journal of Chemometrics, Volume 40, Issue 6, June 2026.
ABSTRACT Partial least squares (PLS) regression is widely used for multivariate calibration in high‐dimensional and collinear settings. However, classical PLS relies on least squares optimization and is therefore sensitive to anomalous observations, leverage points, and structured spectral interferences.
Puneet Mishra
wiley   +1 more source

Cardiovascular β‐Adrenergic Receptor Distribution and Function: Influence of Species, Sex, Age, and Tissue

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Estrogen modulates β‐AR signaling in a context‐dependent manner influenced by species, sex, age, tissue, and vascular health, highlighting challenges in translating findings from experimental models to human cardiovascular physiology. ABSTRACT Cardiovascular diseases remain the leading global cause of morbidity and mortality, with notable sex‐specific ...
Basant Elsaid, Irakli Kopaliani, Birgit Zatschler, Ansam Seif, Stephan Speier, Andreas Deussen   +5 more
wiley   +1 more source

Nano‐Engineered Yogurt as a Functional Delivery Platform: From Encapsulation Technologies to Personalized Nutrition

eFood, Volume 7, Issue 3, June 2026.
Graphical abstract showing nanoencapsulation‐based yogurt fortification, highlighting nanocarrier incorporation, improved storage stability, enhanced bioaccessibility, targeted gastrointestinal release, nutrient absorption, and gut microbiota modulation.
Farhang Hameed Awlqadr, Mohammed N. Saeed, Ammar B. Altemimi, Ahmad F. Hama Sdiq, Othman Abdulrahman Mohammed, Sonia Morya, Syamand Ahmed Qadir, Tablo H. Salih, Khaled Arab   +8 more
wiley   +1 more source

”Not always the magic bullet”—Insufficient seizure control by ketogenic dietary therapies in Glut1 Deficiency Syndrome

Epilepsia Open, Volume 11, Issue 3, Page 847-858, June 2026.
Abstract Objective Ketogenic dietary therapies (KDTs) are the treatment of choice for Glut1 Deficiency Syndrome (Glut1DS), providing dietary ketones as an alternative fuel to the brain and effectively controlling seizures. Recent evidence indicates insufficient seizure control in Glut1DS patients despite adequate KDT and ketosis.
Joerg Klepper, Eva Runkel, Lucia Kiesel
wiley   +1 more source

Mechanophores for Mechano‐Imaging in Polymeric Materials

Helvetica Chimica Acta, Volume 109, Issue 6, June 2026.
Mechanophore‐based mechanochromic systems convert mechanical forces in polymers into optical signals, enabling direct imaging of stress localization and molecular damage. This perspective highlights recent advances in mechanophore design and their use to probe local mechanics across diverse polymer matrices, and concludes by outlining opportunities for
Jess M. Clough
wiley   +1 more source

The MADS symphonies of transcriptional regulation

Frontiers in Plant Science, 2011
Nayelli eMarsch-Martínez, Wenwu eWu, Stefan ede Folter   +2 more
doaj   +1 more source

Significance and Usefulness of High‐Resolution 24‐h Electrocardiographic Parameters in Patients With Coronavirus Disease 2019 After Admission: A Prospective Cohort Study

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
In patients with coronavirus disease 2019 (COVID‐19) without an obvious cardiac disease, ambulatory electrocardiographic markers can be useful in assessing the risk of severe disease. Particularly, simultaneous positivity of late potential (LP) and T wave alternans (TWA) in patients with COVID‐19 was a poorer prognostic factor than LP or TWA alone ...
Motohiro Kimata, Kenichi Hashimoto, Naomi Harada, Yusuke Kawamura, Yoshifumi Kimizuka, Mayuko Kaneko, Nobuaki Kiriu, Yasumasa Sekine, Natsumi Iwabuchi, Tetsuro Kiyozumi, Susumu Matsukuma, Yuji Tanaka, Nobutaka Hirooka   +12 more
wiley   +1 more source