Results 131 to 140 of about 148,513 (305)
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Factura, Madrid, de Francisco Ruiz, Maestro Sillero a Sr. D. José Tellitu y Franco
Factura impresa manuscrita en tinta negraAlcance y contenido: Versa sobre la adquisición de materiales para fabricar sillas de caballerías. Precio expresado en realesEn el membrete: "Francisco Ruiz, Maestro Sillero del Regimiento Coraceros de la Reina ...
Francisco Ruiz, Maestro Sillero
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Factura, 1935 sept. 19, Carabanchel Bajo, de Joaquín Cambra Fayos, Maestro Pocero
, 1935 Factura impresa en negro, manuscrita en tinta negraAlcance y contenido: Versa sobre el coste de 14 tubos de 17 de diámetro. Se indica precio unitario del metro y el coste totalEn la parte superior aparecen impresos el nombre y la dirección del ...
Joaquín Cambra Fayos, Maestro Pocero
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The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Entorno murciano y fulgentino del Obispo Caparrós y López
Alquipir, 1997 Uno de los clérigos cehegineros de más renombre será el Obispo Caparrós y López. De origen humilde, José María Caparrós empezó su formación en Cehegín, aunque pronto marcharía a Murcia, donde gracias a las becas que le fueron otorgadas llegaría a ser ...
Francisco Candel Crespo
doaj
, 2011 [ES] Definición del término Maestro mayor2 en el diccionario Dicter.[EN] Definition of the word Maestro mayor2 in the dictionary ...
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FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Del maestro y el maestro investigador
, 2016 En educación es importante diferenciar si quien se dedica al oficio de enseñar está más en el lado del papel de maestro o de maestro ...
Montealegre Aguilar, Armando
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FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source