Results 201 to 210 of about 748,947 (251)

ELABELA Targets Mitochondria to Modulate Heart Development

open access: yesAdvanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang   +22 more
wiley   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

open access: yesAdvanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda   +8 more
wiley   +1 more source
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J.S. Bach: ¿Maestro de maestros?

2023
Fielmente venerado, reverenciado y emulado a través de los siglos, Johann Sebastian Bach es, aún a día de hoy, una figura omnipresente tanto en el ámbito musical clásico como en el popular. Considerado por muchos como el mejor compositor de todos los tiempos, Bach es uno de los personajes esenciales en el entrelazado de la cultura musical occidental ...
Nuez Suárez, Rebeca   +1 more
openaire   +2 more sources

Penrose maestro

ACM SIGGRAPH 2017 Real Time Live!, 2017
For the first time, Maestro eliminates the old "over-the-shoulder" method of notes delivery from a director, where all the artists are outside VR watching a flat screen with limited context. It provides tools that make reviewing stories as straightforward as traditional reviews, such as synchronized and distributed playback control, laser pointers ...
Devon Penney   +2 more
openaire   +1 more source

In the steps of the “maestro”

The American Journal of Surgery, 1958
T o have one’s work become a turning point in the trend of medical history is a priviIege accorded to very few men. Such, however, was the lot of Sir HaroId GiIIies, and it is fitting that in the evening of his Iife fuI1 acknowledgment shouId be made and thanks accorded for his efforts in the deveIopment of pIastic surgery.
openaire   +2 more sources

¡MAESTRO!

ACM SIGGRAPH 2018 Appy Hour, 2018
We present MaeSTrO, a mobile app for image stylization that empowers users to direct, edit and perform a neural style transfer with creative control. The app uses iterative style transfer, multi-style generative and adaptive networks to compute and apply flexible yet comprehensive style models of arbitrary images at run-time.
Max Reimann   +4 more
openaire   +2 more sources

Hes1: the maestro in neurogenesis

Cellular and Molecular Life Sciences, 2016
The process of neurogenesis is well orchestrated by the harmony of multiple cues in a spatiotemporal manner. In this review, we focus on how a dynamic gene, Hes1, is involved in neurogenesis with the view of its regulation and functional implications.
Sivadasan Bindu, Dhanesh   +2 more
openaire   +2 more sources

Maestros aprendiendo de maestros

2021
Carlos Alberto Muñoz Gutiérrez   +3 more
openaire   +1 more source

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