Results 131 to 140 of about 101,022 (282)

Comparative study on teacher training in supranational perspective: the cases of Germany, France, Italy and Spain

open access: yesTendencias Pedagógicas, 2015
Teacher education, as a key topic to obtain quality education systems, has been internationally studied. This article analyzes, based on national and European documents, the current teacher training systems for infant and primary schools in Germany ...
Eva Ramírez Carpeño
doaj  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

[Historic evocation]. [PDF]

open access: yesRev Fac Cien Med Univ Nac Cordoba, 2023
Acerbi Cremades N.
europepmc   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Fuentes documentales de archivo para el estudio de los arquitectos y maestros que diseñaron y constr

open access: yesAnales de Historia del Arte, 2004
La actual plaza Mayor de la ciudad de Sigüenza fue abierta por deseo del Cardenal don Pedro González de Mendoza, su obispo a finales del siglo XV, y del Cabildo de su catedral. En este artículo, y gracias a las fuentes documentales que se conservan en el
Pilar Martínez Taboada
doaj  

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Maestros [PDF]

open access: yes, 2005
ESP
openaire  

Retraction Note: Explainable artificial intelligence for predictive modeling of student stress in higher education. [PDF]

open access: yesSci Rep
Tariq R   +4 more
europepmc   +1 more source

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