Results 161 to 170 of about 183,970 (268)

Sex Bias in IL-10 Production by Type I Regulatory T Cells Regulated by PI3K/mTOR Signaling. [PDF]

Neurol Neuroimmunol Neuroinflamm
Debonlier A, Kari S, Bucciarelli F, Angles T, Perez-Pestel A, Fébrissy C, Laffont S, Liblau R, Lenfant F, Dunn SE, Guillermet-Guibert J, Astier AL.   +11 more
europepmc   +1 more source

Genome‐wide association study of periodontitis severity and progression

Journal of Periodontology, EarlyView.
Abstract Background To add to the knowledge base of periodontal genomics, we carried out a genome‐wide association study (GWAS) of periodontitis severity and progression among 416 mixed‐ethnicity adult participants of a periodontitis clinical study. Methods Participants were 168 adults (mean age = 50 years, 46% males) with severe periodontitis and 248 ...
Flavia Teles, Ganesh Chandrasekaran, Lynn Martin, Poojan Shrestha, Kevin Moss, Michele Patel, Michael J. Kallan, Camila Furquim, Andrew J. Cucchiara, James D. Beck, Kari E. North, Joseph Glessner, Kimon Divaris   +12 more
wiley   +1 more source

RasGRP1 signaling is required for Vγ2+ thymocyte c-Maf expression and γδT17 lineage programming. [PDF]

J Immunol
Joannou K, Golec DP, Azad AK, Henao Caviedes LM, May JF, Kelly RG, Baldwin TA.   +6 more
europepmc   +1 more source

Association Between Body Mass Index and Depression/Anxiety in an East Asian Population: A Mendelian Randomization Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Obesity and psychiatric disorders are the leading causes of global morbidity. Epidemiological studies suggest a bidirectional link between higher body mass index (BMI) and mental health outcomes, but the direction of causality remains uncertain due to confounding and reverse causation. We performed a Mendelian randomization (MR) analysis using
Perl Han Lee, Szu‐Chia Chen, Chien‐Hung Lee, Jiun‐Hung Geng, Chih‐Hung Ko   +4 more
wiley   +1 more source

Indian-enriched genetic variants are associated with cognitive function. [PDF]

Alzheimers Dement
Abu-Amara H, Zhao W, Li Z, Leung YY, Schellenberg GD, Wang LS, Dey AB, Dey S, Zhou X, Gross AL, Lee J, Kardia SLR, Smith JA.   +12 more
europepmc   +1 more source

Enhancing Crystallinity of Electrospun Polylactic Acid Fibers: Insights into Formation Mechanisms and Property Modulation–A Review

Macromolecular Materials and Engineering, EarlyView.
Controlled processing, nucleating agents, and monitored post‐treatments improve electrospun PLA nanofiber crystallinity. Additionally, stereocomplexation of PLLA and PDLA further enhances this property. Together, these strategies enable scalable, sustainable fabrication of high‐performance PLA nanofibers, expanding their applicability across industrial,
Kardo Khalid Abdullah, Kolos Molnár
wiley   +1 more source

A Genome‐Wide Association Study of Colorectal Cancer Mortality Outcomes Among Individuals of African and Admixture Ancestry

Molecular Carcinogenesis, EarlyView.
ABSTRACT African Americans have the highest colorectal cancer (CRC) mortality rates in the United States. We performed the first genome‐wide association study (GWAS) of overall and CRC‐specific mortality among African Americans with incident CRC to identify genetic contributors to CRC outcomes.
Thomas Lawler, Jirong Long, Rene Welch, Irene Ong, Oluwatoyosi Ogunmuyiwa, Rida A. Khatri, Martha Shrubsole, Shaneda Warren Andersen   +7 more
wiley   +1 more source

Calibrating genome wide significance by minor allele frequency across three major populations. [PDF]

Sci Rep
Vejandla SC, Sadeesh A, Srinivasasainagendra V, Appah M, Tiwari HK.   +4 more
europepmc   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

KRAS Mutation Allele Frequency Dynamics in Plasma Extracellular Vesicles: Association with Survival in Localized Pancreatic Adenocarcinoma. [PDF]

Ann Surg Oncol
Chopra A, He HZ, Milosevic J, Tirukkovalur N, Asmar RE, Nassour I, Nunns G, Chen M, Chen J, Jiang S, Singhi AD, Saeed A, Zhang J, Lee K, Zureikat A, Zheng SY, Paniccia A.   +16 more
europepmc   +1 more source