Results 191 to 200 of about 183,801 (267)

Carbon finance initiatives can provide biodiversity benefits

open access: yesConservation Science and Practice, EarlyView.
We evaluated the biodiversity co‐benefits of a REDD+ initiative in the tropical forests of Sierra Leone and Liberia using a quasi‐experimental study design. Complementary measures from bioacoustics and DNA metabarcoding revealed that REDD+‐financed protected areas were associated with additional biodiversity benefits compared to control areas.
H. S. Sathya Chandra Sagar   +13 more
wiley   +1 more source

Causal role of genetically predicted impairment of branched‐chain amino acid catabolism on insulin secretion and insulin resistance in type 2 diabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Background Elevated branched‐chain amino acids (BCAAs; leucine, valine, isoleucine) are linked to type 2 diabetes (T2D) risk, characterised by defective insulin secretion in pancreatic β‐cell and peripheral insulin resistance. Causative interaction between BCAA metabolism and these two diabetic pathogenesis remains unclear.
Xiangyu Zhou   +4 more
wiley   +1 more source

Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH signalling inhibitors

open access: yesThe FEBS Journal, EarlyView.
NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu   +9 more
wiley   +1 more source

Sex Bias in IL-10 Production by Type I Regulatory T Cells Regulated by PI3K/mTOR Signaling. [PDF]

open access: yesNeurol Neuroimmunol Neuroinflamm
Debonlier A   +11 more
europepmc   +1 more source

Fine‐scale genetic structure in co‐operatively breeding Palmchats (Dulus dominicus) suggests mixed kinship in compound nests

open access: yesIbis, EarlyView.
Fine‐scale genetic structure in animal populations can create opportunities for both kin‐directed co‐operation and kin competition. Knowledge of kinship is therefore key to understanding the selective pressures shaping sociality as well as the effects of social behaviour on local genetic structure.
Joshua B. LaPergola   +2 more
wiley   +1 more source

RasGRP1 signaling is required for Vγ2+ thymocyte c-Maf expression and γδT17 lineage programming. [PDF]

open access: yesJ Immunol
Joannou K   +6 more
europepmc   +1 more source

Genetic Parameters for Novel Feedlot Profitability‐Related Traits in Nelore Cattle

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT This study aimed to estimate (co)variance components and genetic parameters for accumulated profitability (AFP) and profit per kilogram of liveweight gain (PFT), and their relationships with weight at 450 days of age (W450), scrotal circumference at 365 days of age (SC365), age at first calving (AFC), probability of precocious calving at 30 ...
Letícia Pereira   +9 more
wiley   +1 more source

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