Results 211 to 220 of about 103,106 (291)

DBENet: Dual-Branch Encoder Network for brain MRI lesion segmentation. [PDF]

Front Neurol
Zhao Q, Zhang Z, Cao T.
europepmc   +1 more source

Genome‐wide association and interaction analysis for proliferative retinopathy in adults with type 2 diabetes born during famine: The DOLCE study in Ukraine

Acta Ophthalmologica, EarlyView.
Abstract Purpose Proliferative diabetic retinopathy (PDR) is one of the leading causes of blindness in working‐age adults. We have previously shown that the risk of PDR is significantly elevated in individuals with intrauterine exposure to famine. However, the genetic mechanisms mediating this association remain unknown.
Olena Fedotkina, Most Champa Begum, Xuan Tung Trinh, Turkuler Özgumus, Mikael Åkerlund, Peter Nilsson, Leticia Maria Spindola, Valeriya Lyssenko   +7 more
wiley   +1 more source

Navigating tradeoffs in variant filtering for population genetic and demographic inferences to inform management, conservation, and domestication in non-model marine bivalves: a case study in scallop. [PDF]

BMC Genomics
Yin X, Duan S, Bao Z, Hu X.
europepmc   +1 more source

Macular telangiectasia type 2 genetic risk variants associated with clinical characteristics in the Slovenian cohort

Acta Ophthalmologica, EarlyView.
Abstract Purpose Early diagnosis of macular telangiectasia type 2 (MacTel) remains challenging, and the contribution of genetic variation to its clinical heterogeneity is unclear. This study investigated associations between MacTel risk variants and clinical characteristics in a Slovenian cohort.
Ajda Kunčič, Nataša Debeljak, Petra Hudler, Janez Smerkolj, Mojca Urbančič   +4 more
wiley   +1 more source

Relative Mutant Allele Frequency Role in ctDNA-Guided Anti-Epidermal Growth Factor Receptor Rechallenge in Metastatic Colorectal Cancer. [PDF]

JCO Precis Oncol
Yaringaño J, García Pastor P, Salva F, Saoudi González N, Ros J, Baraibar I, Rodríguez Castells M, Salva de Torres C, Mascaró Baselga P, García A, Vaghi C, Vivancos A, Tabernero J, Elez E.   +13 more
europepmc   +1 more source

Review Article: Fibrosis‐4 Index in Steatotic Liver Disease—Past, Present and Future

Alimentary Pharmacology &Therapeutics, EarlyView.
FIB‐4 remains an inexpensive, scalable first‐line triage tool for excluding advanced fibrosis and identifying patients who need second‐line assessment, but it should not be used as a stand‐alone diagnostic or treatment‐selection test. Sequential testing and longitudinal FIB‐4 trajectories may improve risk stratification and prognosis.
Kriti Soni, Vinay Jahagirdar, Omar Albhaisi, Richard K. Sterling, Juan Pablo Arab, Hanna Blaney, Luis Antonio Díaz   +6 more
wiley   +1 more source

Genetic Screening of Colombian Patients With Early-Onset Parkinson Disease. [PDF]

Neurol Genet
Franz TM, Gavrielatos M, Wijaya Y, Beasley AI, Kim-Hellmuth S, Strongosky AJ, Moreno-López CL, Ross OA, Wszolek ZK, Cerquera-Cleves C.   +9 more
europepmc   +1 more source

CD47 promotes myeloma cell growth through JAK–STAT3/MYC signalling and is targetable by ruxolitinib

British Journal of Haematology, EarlyView.
Summary Cluster of differentiation 47 (CD47), a ‘don't eat me’ immune checkpoint receptor, is frequently overexpressed on multiple myeloma (MM) cells and contributes to immune evasion. While its immune regulatory function is well established, the intrinsic oncogenic role of CD47 remains poorly understood.
Omar Faruq, Deepak Iyer, Patrick Wang, Mariusz Shrestha, Cuihong Wei, Aaron D. Schimmer, Hong Chang   +6 more
wiley   +1 more source

Dynamic evolution of FLC/MAF-like genes accompanying Brassicaceae radiation. [PDF]

Ann Bot
Zhao BY, Zhou SZ, Liu J, Zhong MC, Dong X, Li DZ, Hu JY.   +6 more
europepmc   +1 more source