American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
wiley +1 more source
Mangiferin: Analgesic properties in neuropathic pain, molecular docking and meta-analysis
Phytomedicine Plus, 2022 Aim: : To investigate the analgesic effects of mangiferin (MAF) in experimental neuropathic pain (NPP) models and underlying mechanism. Methods: : Databases including Pubmed, Web of Science, Embase, Cochrane Library, China national knowledge ...
Bo-tao Chang +8 more
doaj +1 more source
Detecting epistasis via Markov bases [PDF]
, 2010 Rapid research progress in genotyping techniques have allowed large genome-wide association studies. Existing methods often focus on determining associations between single loci and a specific phenotype.
Malaspinas, Anna-Sapfo, Uhler, Caroline
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The ubiquitin-conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis
Journal of Hematology & Oncology, 2017 Background UBE2O is proposed as a ubiquitin-conjugating enzyme, but its function was largely unknown. Methods Mass spectrometry was applied to identify c-Maf ubiquitination-associated proteins.
Yujia Xu +10 more
doaj +1 more source
Novel Process Modeling of Magnetic-Field Assisted Finishing (MAF) with Rheological Properties
Lubricants, 2023 The performance of a magnetic-field-assisted finishing (MAF) process, an advanced surface finishing process, is severely affected by the rheological properties of an MAF brush.
Bibek Poudel +4 more
doaj +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
c-MAF, a Swiss Army Knife for Tolerance in Lymphocytes
Frontiers in Immunology, 2020 Beyond its well-admitted role in development and organogenesis, it is now clear that the transcription factor c-Maf has owned its place in the realm of immune-related transcription factors.
Claire Imbratta +3 more
doaj +1 more source
Investment opportunities in kiwifruit processing : a case study in product development that considers the advisory role of the New Zealand Ministry of Agriculture and Fisheries : a thesis in partial fulfilment of the requirements for the degree of Master of Agricultural Science at Massey University [PDF]
, 1985 This thesis is set in the context of the Economic Section of the Advisory Services Division of the New Zealand Ministry of Agriculture and Fisheries (MAF). MAF provides management advice to farmers and horticulturalists on what and how to produce. The
Cloughley, Brian Alexander
core
Low-density genotype panel for both parentage verification and discovery in a multi-breed sheep population [PDF]
, 2019 peer-reviewedThe generally low usage of artificial insemination and single-sire mating in sheep, compounded by mob lambing (and lambing outdoors), implies that parentage assignment in sheep is challenging.
Berry, Donagh +4 more
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β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source