Results 31 to 40 of about 103,106 (291)

Transcription factor c-Maf deletion improves streptozotocin-induced diabetic nephropathy by directly regulating Sglt2 and Glut2

JCI Insight, 2023
The transcription factor c-Maf has been widely studied and has been reported to play a critical role in embryonic kidney development; however, the postnatal functions of c-Maf in adult kidneys remain unknown as c-Maf–null C57BL/6J mice exhibit embryonic ...
Mitsunori Fujino, Naoki Morito, Takuto Hayashi, Masami Ojima, Shun Ishibashi, Akihiro Kuno, Seizo Koshiba, Kunihiro Yamagata, Satoru Takahashi   +8 more
doaj   +1 more source

Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis

Cell Communication and Signaling, 2021
Background The oncogenic transcript factor c-Maf is stabilized by the deubiquitinase Otub1 and promotes myeloma cell proliferation and confers to chemoresistance.
Tong Sun, Yujia Xu, Zhuan Xu, Biyin Cao, Zubin Zhang, Qi Wang, Yan Kong, Xinliang Mao   +7 more
doaj   +1 more source

Ausbildungstyp oder Ausbildungsgang? Kritische Überlegungen zur Frage der "richtigen" Struktur der Ausbildung von Lehrerinnen und Lehrern

Beiträge zur Lehrerinnen- und Lehrerbildung, 1997
Auf der Folie der aktuellen Reformdiskussionen um die zukünftige Struktur der schweizerischen Lehrerinnen- und Lehrerbildung wird in diesem Beitrag kritisch nach dem Bezugspunkt dieser Diskussionen gefragt.
Martin Wild-Mäf
doaj   +1 more source

The incidence and risk factors of meconium amniotic fluid in singleton pregnancies: an experience of a tertiary hospital in Iran

BMC Pregnancy and Childbirth, 2022
Background Several common maternal or neonatal risk factors have been linked to meconium amniotic fluid (MAF) development; however, the results are contradictory, depending on the study.
Mitra Shekari, Malihe Shirzadfard Jahromi, Amene Ranjbar, Vahid Mehrnoush, Fatemeh Darsareh, Nasibeh Roozbeh   +5 more
doaj   +1 more source

Reciprocal regulation of C-Maf tyrosine phosphorylation by Tec and Ptpn22. [PDF]

PLoS ONE, 2015
C-Maf plays an important role in regulating cytokine production in TH cells. Its transactivation of IL-4 is optimized by phosphorylation at Tyr21, Tyr92, and Tyr131. However, the molecular mechanism regulating its tyrosine phosphorylation remains unknown.
Chih-Chun Liu, Chen-Yen Lai, Wei-Feng Yen, Yu-Hsien Lin, Hui-Hsin Chang, Tzong-Shyuan Tai, Yu-Jung Lu, Hsiao-Wei Tsao, I-Cheng Ho, Shi-Chuen Miaw   +9 more
doaj   +1 more source

Tumor-suppressive role of the musculoaponeurotic fibrosarcoma gene in colorectal cancer

iScience, 2023
Summary: Somatic cell reprogramming using the microRNAs miR-200c, miR-302s, and miR-369s leads to increased expression of cyclin-dependent kinase inhibitors in human colorectal cancer (CRC) cells and suppressed tumor growth. Here, we investigated whether
Hiroaki Itakura, Tsuyoshi Hata, Daisuke Okuzaki, Koki Takeda, Kenji Iso, Yamin Qian, Yoshihiro Morimoto, Tomohiro Adachi, Haruka Hirose, Yuhki Yokoyama, Takayuki Ogino, Norikatsu Miyoshi, Hidekazu Takahashi, Mamoru Uemura, Tsunekazu Mizushima, Takao Hinoi, Masaki Mori, Yuichiro Doki, Hidetoshi Eguchi, Hirofumi Yamamoto   +19 more
doaj   +1 more source

MAF-1 and climate indices.

, 2016
Time-series (1950–2012) comparison of the low-frequency signal in upwelling activity MAF-1 (upper panel), the Multivariate ENSO index MEI (b); the North Pacific Oscillation index NOI (c), and the Pacific Decadal Oscillation PDO (d).
Romeo Saldívar-Lucio (3366383), Emanuele Di Lorenzo (182138), Héctor Villalobos (3366377), Pablo Del Monte-Luna (3366386), Miguel Nakamura (3366380), Daniel Lluch-Cota (3366374)   +5 more
core   +1 more source

Differentiation of IL-17-Producing Invariant Natural Killer T Cells Requires Expression of the Transcription Factor c-Maf

Frontiers in Immunology, 2017
c-Maf belongs to the large Maf family of transcription factors and plays a key role in the regulation of cytokine production and differentiation of TH2, TH17, TFH, and Tr1 cells.
Jhang-Sian Yu, Michito Hamada, Shigeo Ohtsuka, Keigyou Yoh, Satoru Takahashi, Shi-Chuen Miaw   +5 more
doaj   +1 more source

filtered-geno-0.2-maf-0.05-mind-0.9

, 2018
filtered-geno-0.2-maf-0.05-mind-0.
Gemmell, Neil J., Helen R. Taylor (5032385), Taylor, Helen R., Dussex, Nicolas, Stovall, Willam R., Nicolas Dussex (696163), Clarke, Shannon M., Neil J. Gemmell (7909604), Ken G. Dodds (8140197), Shannon M. Clarke (8140200), Rutherford, Kim, Willam R. Stovall (8140194), Dodds, Ken G., Kim Rutherford (45266)   +13 more
core   +1 more source

Activation of connective tissue growth factor gene by the c-Maf and Lc-Maf transcription factors [PDF]

, 2005
The Maf family of transcription factors is expressed during development of various organs and tissues, and is involved in a variety of developmental and cellular differentiation processes. We previously found that c-maf and mafB are strongly expressed in
Imaki, Junko, Sakai, Masaharu, Omoteyama, Kazuki, Ikeda, Hiromi   +3 more
core   +1 more source