Results 31 to 40 of about 86,998 (259)

Reciprocal regulation of C-Maf tyrosine phosphorylation by Tec and Ptpn22. [PDF]

PLoS ONE, 2015
C-Maf plays an important role in regulating cytokine production in TH cells. Its transactivation of IL-4 is optimized by phosphorylation at Tyr21, Tyr92, and Tyr131. However, the molecular mechanism regulating its tyrosine phosphorylation remains unknown.
Chih-Chun Liu, Chen-Yen Lai, Wei-Feng Yen, Yu-Hsien Lin, Hui-Hsin Chang, Tzong-Shyuan Tai, Yu-Jung Lu, Hsiao-Wei Tsao, I-Cheng Ho, Shi-Chuen Miaw   +9 more
doaj   +1 more source

Differentiation of IL-17-Producing Invariant Natural Killer T Cells Requires Expression of the Transcription Factor c-Maf

Frontiers in Immunology, 2017
c-Maf belongs to the large Maf family of transcription factors and plays a key role in the regulation of cytokine production and differentiation of TH2, TH17, TFH, and Tr1 cells.
Jhang-Sian Yu, Michito Hamada, Shigeo Ohtsuka, Keigyou Yoh, Satoru Takahashi, Shi-Chuen Miaw   +5 more
doaj   +1 more source

MAFCO: A Compression Tool for MAF Files

PLOS ONE, 2015
In the last decade, the cost of genomic sequencing has been decreasing so much that researchers all over the world accumulate huge amounts of data for present and future use. These genomic data need to be efficiently stored, because storage cost is not decreasing as fast as the cost of sequencing.
Matos, Luís M. O., Neves, António J. R., Pratas, Diogo, Pinho, Armando J.   +3 more
openaire   +5 more sources

MAF-PLL With Phase-Lead Compensator [PDF]

IEEE Transactions on Industrial Electronics, 2015
A basic approach to improve the filtering capability of a standard phase-locked loop (PLL) is to incorporate a moving average filter (MAF) into its control loop. This improvement, however, is at the cost of a slow transient response for the PLL, which is undesirable in most applications.
Saeed Golestan, Josep M. Guerrero, Abdullah M. Abusorrah   +2 more
openaire   +2 more sources

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

The ubiquitin-conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis

Journal of Hematology & Oncology, 2017
Background UBE2O is proposed as a ubiquitin-conjugating enzyme, but its function was largely unknown. Methods Mass spectrometry was applied to identify c-Maf ubiquitination-associated proteins.
Yujia Xu, Zubin Zhang, Jie Li, Jiefei Tong, Biyin Cao, Paul Taylor, Xiaowen Tang, Depei Wu, Michael F. Moran, Yuanying Zeng, Xinliang Mao   +10 more
doaj   +1 more source

Novel Process Modeling of Magnetic-Field Assisted Finishing (MAF) with Rheological Properties

Lubricants, 2023
The performance of a magnetic-field-assisted finishing (MAF) process, an advanced surface finishing process, is severely affected by the rheological properties of an MAF brush.
Bibek Poudel, Hoa Nguyen, Guangchao Song, Patrick Kwon, Haseung Chung   +4 more
doaj   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

c-MAF, a Swiss Army Knife for Tolerance in Lymphocytes

Frontiers in Immunology, 2020
Beyond its well-admitted role in development and organogenesis, it is now clear that the transcription factor c-Maf has owned its place in the realm of immune-related transcription factors.
Claire Imbratta, Hind Hussein, Fabienne Andris, Grégory Verdeil   +3 more
doaj   +1 more source