Results 41 to 50 of about 103,106 (291)

MAFCO: A Compression Tool for MAF Files

PLOS ONE, 2015
In the last decade, the cost of genomic sequencing has been decreasing so much that researchers all over the world accumulate huge amounts of data for present and future use. These genomic data need to be efficiently stored, because storage cost is not decreasing as fast as the cost of sequencing.
Matos, Luís M. O., Neves, António J. R., Pratas, Diogo, Pinho, Armando J.   +3 more
openaire   +5 more sources

Whole-mount and cryosection in situ hybridization exhibit ectopic expression of Six3 when L-Maf, but not c-Maf and MafB, is misexpressed

, 2011
Electroporated chick embryos with L-Maf (-), c-Maf (-), MafB (-), and empty vector (,) were analyzed whole and in sections at stage 16 to follow the expression of Six3.
Atsuyo Urano (52850), Hasan Mahmud Reza (52849), Kunio Yasuda (52851), Naoko Shimada (19632)   +3 more
core   +1 more source

Generalized Dystonia With Cervical Predominance in a Patient With a De Novo TCF20 Variant

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT TCF20 has been implicated in developmental delay and intellectual disability, with dystonia reported less frequently. We describe a woman in her early twenties with childhood‐onset learning difficulties, progressive dysarthria, tremor, and generalized dystonia with marked cervical predominance, associated with a de novo TCF20 frameshift ...
Melisa Kilic, Petr Dusek, Ibrahim Kamaci, Bahar Gulmez, Gul Yalcin Cakmakli, Ersin Tan, Sibel Ugur Iseri, Zuhal Yapici   +7 more
wiley   +1 more source

The ubiquitin-conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis

Journal of Hematology & Oncology, 2017
Background UBE2O is proposed as a ubiquitin-conjugating enzyme, but its function was largely unknown. Methods Mass spectrometry was applied to identify c-Maf ubiquitination-associated proteins.
Yujia Xu, Zubin Zhang, Jie Li, Jiefei Tong, Biyin Cao, Paul Taylor, Xiaowen Tang, Depei Wu, Michael F. Moran, Yuanying Zeng, Xinliang Mao   +10 more
doaj   +1 more source

Novel Process Modeling of Magnetic-Field Assisted Finishing (MAF) with Rheological Properties

Lubricants, 2023
The performance of a magnetic-field-assisted finishing (MAF) process, an advanced surface finishing process, is severely affected by the rheological properties of an MAF brush.
Bibek Poudel, Hoa Nguyen, Guangchao Song, Patrick Kwon, Haseung Chung   +4 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

Mangiferin: Analgesic properties in neuropathic pain, molecular docking and meta-analysis

Phytomedicine Plus, 2022
Aim: : To investigate the analgesic effects of mangiferin (MAF) in experimental neuropathic pain (NPP) models and underlying mechanism. Methods: : Databases including Pubmed, Web of Science, Embase, Cochrane Library, China national knowledge ...
Bo-tao Chang, Hui-zhong Jiang, Yi-jing Wei, Qiu-ju Gong, Dan Yu, Zhi-yu Dong, Jun Luo, Ying Gao, Qi Yao   +8 more
doaj   +1 more source

Microfluidic Droplet Plate Preserving Single Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Morphology and Function

Advanced Materials Technologies, EarlyView.
We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang, Rachel P. White, Yashasvi Tharani, Michael A. Finocchiaro, Leona M. Ripple, Maksymilian Prondzynski, Tania Konry, Vassilios J. Bezzerides   +7 more
wiley   +1 more source

Efferocytosis-associated Mrc1+Gas6+ macrophages are linked to abdominal aortic aneurysm progression through ERK-associated dysfunction

Frontiers in Immunology
BackgroundAbdominal aortic aneurysm (AAA) is a progressive vascular disease characterized by chronic inflammation, extracellular matrix degradation, and aortic wall remodeling, yet effective pharmacological therapies remain lacking and how macrophage ...
Wenxuan Xiang, Xiaohong Song, Xiangyu Xian, Hao Zhou, Bingli Xu, Lei Zhou, Dan Yang, Yuehong Zheng, Yuehong Zheng, Yuehong Zheng   +9 more
doaj   +1 more source