Results 61 to 70 of about 1,059,372 (334)

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Research advances of magnesium and magnesium alloys globally in 2023

Journal of Magnesium and Alloys
Magnesium materials have attracted the attention of many researchers, and the related research is expanding. This article summarizes the advance in the research and development of magnesium materials globally in 2023 from bibliometric and scientific ...
Jia She, Jing Chen, Xiaoming Xiong, Yan Yang, Xiaodong Peng, Daolun Chen, Fusheng Pan   +6 more
doaj   +1 more source

Spatio-Temporal Variation of Soil Phosphorus and Its Implications for Future Pomelo Orcharding System Management: A Model Prediction From Southeast China From 1985–2100

Frontiers in Environmental Science, 2022
Phosphorus (P) is a non-renewable source, requires in large amount for maintaining better crop growth and development. The excessive P fertilizer contributes to the accumulation of P in the soil and results in increased soil total P and Olsen P. However,
Xiaojun Yan, Guohua Li, Guohua Li, Weiqiang Zhang, Muhammad Atif Muneer, Wenjia Yu, Changcheng Ma, Liangquan Wu   +7 more
doaj   +1 more source

Lightweight magnesium-lithium alloys show promise [PDF]

, 1964
Evaluation tests show that magnesium-lithium alloys are lighter and more ductile than other magnesium alloys.
Adams, W. T., Cataldo, C. E.
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Enhancing damping properties of Mg–Sn–Y alloys: The role of metastable clustering

Journal of Materials Research and Technology
The damping properties of Mg–Sn–Y alloys with varied Sn/Y atomic ratios and heat-treatment processes have been studied. In the as-cast state, the alloy with a Sn/Y ratio of 3:1 exhibits the highest damping property in the low strain region due to the low
Xun Chen, Lunchao Zhang, Yuan Yuan, Tao Chen, Jun Wang, Ligang Zhang, Liang Wu, Xianhua Chen, Jingfeng Wang, Fusheng Pan   +9 more
doaj   +1 more source

Determination of hydroxyl content in impure magnesium oxide [PDF]

, 1970
Three-step thermal process quantitatively determines the hydroxyl content in samples of magnesium oxide.
Blosser, E. R., Hall, E. H., Iden, R. B.
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Metal adsorption by quasi cellulose xanthogenates derived from aquatic and terrestrial plant materials [PDF]

, 2011
The FTIR spectra, SEM-EDXA and copper adsorption capacities of the raw plant materials, alkali treated straws and cellulose xanthogenate derivatives of Eichhornia crassipes shoot, rape straw and corn stalk were investigated.
Deng, Li, Ge, Xuan, Hua, Yumei, Langdon, Alan, Zhao, Jianwei, Zhou, Wenbing, Zhu, Duanwei   +6 more
core   +2 more sources

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source