Results 61 to 70 of about 728,274 (341)

A Novel Asymmetric Diffusion Path for Superior Ion Dynamic in High‐Voltage Mg‐Based Hybrid Batteries

open access: yesAdvanced Science
Magnesium‐based batteries have garnered significant attention due to their high energy density, excellent intrinsic safety, and low cost. However, the application process has been hindered by the high Mg2+ ions diffusion barrier in solid‐state structures
Kaifeng Huang   +9 more
doaj   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Reduction per pass effect on texture traits and mechanical anisotropy of Mg–Al–Zn–Mn–Ca alloy subjected to unidirectional and cross rolling

open access: yesJournal of Materials Research and Technology, 2020
In this work, the effect of thermomechanical processing schedules on microstructure, texture and mechanical anisotropy of Mg-1.64Al-0.84Zn-0.38Mn-0.49Ca (AZMX1100, wt.%) alloy was investigated.
Qinghang Wang   +7 more
doaj  

Applications of magnesium alloys for aerospace: A review

open access: yesJournal of Magnesium and Alloys, 2023
Jingying Bai   +7 more
semanticscholar   +1 more source

XV.—On magnesium [PDF]

open access: yesJ. Chem. Soc.
n ...
Wanklyn, J. Alfred, Chapman, Ernest T.
openaire   +3 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Renal control of calcium, phosphate, and magnesium homeostasis.

open access: yesAmerican Society of Nephrology. Clinical Journal, 2015
Calcium, phosphate, and magnesium are multivalent cations that are important for many biologic and cellular functions. The kidneys play a central role in the homeostasis of these ions. Gastrointestinal absorption is balanced by renal excretion. When body
J. Blaine, M. Chonchol, M. Levi
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

MAGNESIUM AS A SEDATIVE [PDF]

open access: yesAmerican Journal of Psychiatry, 1922
It was shown by Meltzer and Auer in 1905 that the primary effect of magnesium upon the nerve cells is that of paralysis without any preceding excitation. The effect seemed to be exclusively of an inhibitory character. They injected subcutaneously into rabbits varying amounts of a 25 per cent solution of magnesium sulphate.
openaire   +3 more sources

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

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