Results 61 to 70 of about 728,274 (341)
A Novel Asymmetric Diffusion Path for Superior Ion Dynamic in High‐Voltage Mg‐Based Hybrid Batteries
Advanced ScienceMagnesium‐based batteries have garnered significant attention due to their high energy density, excellent intrinsic safety, and low cost. However, the application process has been hindered by the high Mg2+ ions diffusion barrier in solid‐state structures
Kaifeng Huang +9 more
doaj +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Journal of Materials Research and Technology, 2020 In this work, the effect of thermomechanical processing schedules on microstructure, texture and mechanical anisotropy of Mg-1.64Al-0.84Zn-0.38Mn-0.49Ca (AZMX1100, wt.%) alloy was investigated.
Qinghang Wang +7 more
doaj
Applications of magnesium alloys for aerospace: A review
Journal of Magnesium and Alloys, 2023 Jingying Bai +7 more
semanticscholar +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Renal control of calcium, phosphate, and magnesium homeostasis.
American Society of Nephrology. Clinical Journal, 2015 Calcium, phosphate, and magnesium are multivalent cations that are important for many biologic and cellular functions. The kidneys play a central role in the homeostasis of these ions. Gastrointestinal absorption is balanced by renal excretion. When body
J. Blaine, M. Chonchol, M. Levi
semanticscholar +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
American Journal of Psychiatry, 1922 It was shown by Meltzer and Auer in 1905 that the primary effect of magnesium upon the nerve cells is that of paralysis without any preceding excitation. The effect seemed to be exclusively of an inhibitory character. They injected subcutaneously into rabbits varying amounts of a 25 per cent solution of magnesium sulphate.
openaire +3 more sources
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source