Results 51 to 60 of about 79,773 (299)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Lightweight magnesium-lithium alloys show promise [PDF]

open access: yes, 1964
Evaluation tests show that magnesium-lithium alloys are lighter and more ductile than other magnesium alloys.
Adams, W. T., Cataldo, C. E.
core   +1 more source

Rare Earths and the Balance Problem: How to Deal with Changing Markets? [PDF]

open access: yes, 2018
The balance between the market demand and the natural abundance of the rare-earth elements (REEs) in ores, often referred to as the Balance Problem (or the Balancing Problem), is a major issue for REE suppliers.
Binnemans, Koen   +3 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

A Novel Asymmetric Diffusion Path for Superior Ion Dynamic in High‐Voltage Mg‐Based Hybrid Batteries

open access: yesAdvanced Science
Magnesium‐based batteries have garnered significant attention due to their high energy density, excellent intrinsic safety, and low cost. However, the application process has been hindered by the high Mg2+ ions diffusion barrier in solid‐state structures
Kaifeng Huang   +9 more
doaj   +1 more source

A study on factors affecting the degradation of magnesium and a magnesium-yttrium alloy for biomedical applications. [PDF]

open access: yes, 2013
Controlling degradation of magnesium or its alloys in physiological saline solutions is essential for their potential applications in clinically viable implants. Rapid degradation of magnesium-based materials reduces the mechanical properties of implants
Johnson, Ian, Liu, Huinan
core   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Texture Evolution of AZ31 Magnesium Alloy Sheet at High Strain Rates [PDF]

open access: yes, 2010
In the current contribution the mechanical behaviour at high strain rates of AZ31 magnesium alloy sheet is studied. Uniaxial deformation properties were studied by means of tensile split Hopkinson pressure bar (SHPB) at different temperatures.
Dudamell, N.V.   +6 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Nondestructive spot test method for magnesium and magnesium alloys [PDF]

open access: yes, 1973
A method for spot test identification of magnesium and various magnesium alloys commonly used in aerospace applications is described. The spot test identification involves color codes obtained when several drops of 3 M hydrochloric acid are placed on the
Wilson, M. L.
core   +1 more source

Home - About - Disclaimer - Privacy