Results 21 to 30 of about 21,571 (265)

Disruption prediction for future tokamaks using parameter-based transfer learning

Communications Physics, 2023
Tokamaks are the most promising way for nuclear fusion reactors. Disruption in tokamaks is a violent event that terminates a confined plasma and causes unacceptable damage to the device.
Wei Zheng, Fengming Xue, Zhongyong Chen, Dalong Chen, Bihao Guo, Chengshuo Shen, Xinkun Ai, Nengchao Wang, Ming Zhang, Yonghua Ding, Zhipeng Chen, Zhoujun Yang, Biao Shen, Bingjia Xiao, Yuan Pan   +14 more
doaj   +1 more source

Layer-structured Cr/Cr x N coating via electroplating-based nitridation achieving high deuterium resistance as the hydrogen permeation barrier

Journal of Advanced Ceramics, 2022
Hydrogen isotope permeation through structural materials is a key issue for developing nuclear fusion energy, which will cause fuel loss and radioactive pollution.
Liyu Zheng, Heping Li, Jun Zhou, Xinluo Tian, Zhongyang Zheng, Long Wang, Xinyun Wang, Youwei Yan   +7 more
doaj   +1 more source

WEST: Impact of wall conditions on impurity sources and core contamination for various plasma shapes*

Nuclear Materials and Energy
WEST’s unique characteristics with nearly all tungsten (W) PFCs offer an ideal platform to study plasma operations and plasma scenario development for long-pulsed, actively cooled, nearly all W-PFC tokamaks [1]. W erosion/redeposition of the PFCs and the
A. Grosjean, D.C. Donovan, P. Devynck, Fedorczak, A. Gallo, J. Gaspar, J. Gerardin, J.P. Gunn, C. Guillemaut, B. Guillermin, C.A. Johnson, S.R. Kosslow, P. Manas, S. Mazzi, D. Moiraf, P. Moreau, B. Putra, N. Rivals, E.A. Unterberg   +18 more
doaj   +1 more source

Calorimetry measurement for energy balance and energy distribution in WEST for L-mode plasmas

Nuclear Fusion
This paper presents the energy balance of 602 pulses from four different experimental campaigns for the WEST tokamak. Different magnetic configurations have been studied, with lower single null (LSN) and upper single null (USN) configuration with ...
J. Gaspar, J. Gerardin, Y. Corre, J. Daumas, N. Fedorczak, V. Lamaison, C. Bourdelle, G. Ciraolo, A. Ekedahl, A. Gallo, N. Rivals, E. Tsitrone, the WEST Team   +12 more
doaj   +1 more source

Identification of a double decay length (λqt) heat flux deposition shape with embedded thermal measurement and neural network

Nuclear Materials and Energy
The estimation of the heat flux density distribution profiles in tokamak devices is a very important research topic for edge plasma physics purposes and also to ensure the safety of the machine.
Y. Anquetin, J. Gaspar, Y. Corre, JL. Gardarein, J. Gerardin, P. Malard, F. Rigollet, Q. Tichit, E. Tsitrone   +8 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Plasma heat load in the toroidal gaps of the ITER-like plasma facing units in WEST tokamak

Nuclear Materials and Energy
The heat load deposited in the toroidal gaps between two tungsten monoblocks remains an open problem to prepare safe and powerful experiments in ITER.
Q. Tichit, M.H. Aumeunier, Y. Corre, R. Dejarnac, L. Dubus, J. Gaspar, J. Gerardin, A. Grosjean, J.P. Gunn, A. Juven, K. Krieger, A. Podolník, E. Tsitrone   +12 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source