Results 181 to 190 of about 7,982 (306)

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source

Taming harmful bursts and heat flux in high-confinement tokamak plasmas. [PDF]

Nat Commun
Hu QM, Wang HQ, Navarro M, Wang HH, Eldon D, Gu S, Ma XX, Frerichs H, Scotti F, Wang L, Wilcox RS, Wilks TM, Bortolon A, Ceelen L, Effenberg F, Gong XZ, Jia MN, Kim SK, Lasnier CJ, Leonard AW, Li KD, Logan NC, Ma Q, Maingi R, Meng LY, Moser AL, Osborne TH, Paz-Soldan C, Shafer MW, Sun YW, Yang SM, Ye C.   +31 more
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Occupancy-Aware Neural Distance Perception for Manipulator Obstacle Avoidance in the Tokamak Vacuum Vessel. [PDF]

Sensors (Basel)
Li F, Chou W.
europepmc   +1 more source

Transferable Deep Reinforcement Learning With Edge‐Contour‐Depth Fusion for Autonomous Wireless Capsule Endoscopy Navigation

Advanced Science, EarlyView.
This study presents an anatomical landmark‐guided DRL framework for autonomous wireless capsule endoscopy navigation. Using a lightweight edge‐contour‐depth fusion module, it achieves over 97% coverage across diverse gastric anatomies. To ensure reliability, a two‐stage sim‐to‐real pipeline with an adaptive dynamic programming controller mitigates ...
Haoxuan Wu, Haitao Gao, Qingyang Liu, Sishen Yuan, Haiyang Fang, Mingwu Su, Baijia Liang, Yongzun Yang, Long Bai, Wenzhen Dong, Dihong Xie, Shijian Su, Jiewen Lai, Shing Shin Cheng, Zhen Li, Xiuli Zuo, Hongliang Ren   +16 more
wiley   +1 more source

Detection of Small Debonding Defects in Metal-Rubber Bonded Structures Using an Enhanced EMAT and Multi-Feature Fusion Imaging. [PDF]

Sensors (Basel)
Fang Y, Wang X, Qu Y, Chen H, Chen Z.
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Steric confinement-induced emission probe for monitoring protein conformations in live cells. [PDF]

Commun Chem
Jia H, Yang L, Yang Y, Liu H, Liu J, Shang C, Di Z, He B, Zhang K.   +8 more
europepmc   +1 more source

Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal

Advanced Science, EarlyView.
We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao, Yi Hou, Jie Zhang, Bo Wang, Minghui Guo, Hua Qu, Wei Rao, Jing Liu   +7 more
wiley   +1 more source

Multi-scale Interaction Mechanism for Edge-Localized-Mode Suppression in the Tokamak Edge. [PDF]

Nat Commun
Li Z, Diamond PH, Chen X, Khabanov F, Xu X, Hong RJ, Chan VS, Muscatello CM, Zeng L, Yu GY, Rhodes T, McKee GR, Yan Z, Austin ME.   +13 more
europepmc   +1 more source