Results 41 to 50 of about 3,441,575 (300)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Research of spatial distribution of electromagnetic fields of industrial frequency in the central part of the city of Saratov [PDF]

Известия Саратовского университета. Новая серия: Серия Науки о Земле
The cartographic research of electric and magnetic fields of industrial frequency in the central part of Saratov was performed. Measurements by means of the Gigahertz Solutions ME 3830 B M/E Analyser were executed in the 177 points within the built-up ...
Sturman, Vladimir I., Loginova, Marina Pavlovna   +1 more
doaj   +1 more source

Practical analysis of 3-D dynamic nonlinear magnetic field using time-periodic finite element method [PDF]

, 1995
A practical 3-D finite element method using edge elements for analyzing stationary nonlinear magnetic fields with eddy currents in electric apparatus, in which the flux interlinking the voltage winding is given, has been proposed.
Nakata, Takayoshi, Takahashi, Norio, Zhu, Hui Ling, Fujiwara, Koji, Muramatsu, Kazuhiro, Ohashi, Hiromitsu   +5 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Accurate polarization calibration of FAST spectral data for measurements of Zeeman splittings of OH megamasers in IRAS 02524+2046

Astronomy & Astrophysics
Context. An accurate polarization calibration is essential for a spectral data analysis and Zeeman splitting measurements. Two anomalies challenge our understanding of OH megamasers in IRAS 02524+2046: an unexplained 1667/1665 MHz flux-ratio deviation ...
Hou L. G., Gao X. Y., Hong T., Han J. L.
doaj   +1 more source

Star Formation and Galaxy Dynamo Equations with Random Coefficients

Open Astronomy, 2015
We study the influence of star formation on magnetic field in galaxies. Two approaches have been used to describe this mechanism. The first one uses some averaged approximate kinematic characteristics that appear in the galactic dynamo equations.
Mikhailov E. A., Modyaev I. I.
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Magnetic fields in galaxies [PDF]

Proceedings of the International Astronomical Union, 2005
AbstractThe origin and evolution of magnetic fields in the Universe is a cosmological problem. Although exotic mechanisms for magneotgenesis cannot be ruled out, galactic magnetic fields could have been seeded by magnetic fields from stars and accretion disks, and must be continuously regenerated due to the ongoing replacement of the interstellar ...
openaire   +1 more source