Results 11 to 20 of about 202,156 (302)

A Review of Diffusion Magnetic Resonance Imaging in Characterization of Breast Cancers

open access: yesFrontiers in Biomedical Technologies, 2022
Diffusion Magnetic Resonance Imaging (dMRI) has widely been used as a part of breast MRI protocols throughout the world, providing valuable information about breast tissue structures.
Mohammad Reza Alviri   +4 more
doaj   +1 more source

Differential Diagnosis Among Alzheimer's Disease, Mild Cognitive Impairment, and Normal Subjects Using Resting-State fMRI Data Extracted from Multi Subject Dictionary Learning Atlas

open access: yesFrontiers in Biomedical Technologies, 2022
Purpose: A powerful imaging method for evaluating brain patches is resting-state functional magnetic resonance imaging, in which the subject is at rest. Artificial neural networks are one of the several Alzheimer's disease analysis and diagnosis methods
Farzad Alizadeh   +7 more
doaj   +1 more source

Ironsmith: An automated pipeline for QSM-based data analyses

open access: yesNeuroImage, 2022
Quantitative susceptibility mapping (QSM) is an MRI-based, computational method for anatomically localizing and measuring concentrations of specific biomarkers in tissue such as iron.
Valentinos Zachariou   +3 more
doaj   +1 more source

Development and Applications of HDX-NMR and HDX-MS in Protein Structure and Dynamics Research

open access: yesChinese Journal of Magnetic Resonance
Hydrogen-deuterium exchange nuclear magnetic resonance (HDX-NMR) and hydrogen-deuterium exchange mass spectrometry (HDX-MS) are key techniques for studying protein structure and dynamics, and have been widely applied to analyzing protein conformational ...
ZHANG Yuanyuan   +5 more
doaj   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

Multivariate metal-organic frameworks enable chemical shift-encoded MRI with femtomolar sensitivity for biological systems

open access: yesNature Communications
Fluorescent molecules with specific target moieties are essential for histopathological analysis, but their limited tissue penetration depth makes in vivo, in situ color encoding analysis challenging.
Qingbin Zeng   +15 more
doaj   +1 more source

High-resolution two-photon fluorescence microscope imaging of nanodiamonds containing NV color centers

open access: yesResults in Physics, 2022
Fluorescent nanodiamonds containing nitrogen-vacancy (NV) color centers play an important role in nanoscale sensing for their unique properties, including extraordinary photon stability, bio-compatibility, and chemical inertness at room temperature.
Zhiping Ju   +5 more
doaj   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Limosilactobacillus reuteri normalizes blood–brain barrier dysfunction and neurodevelopment deficits associated with prenatal exposure to lipopolysaccharide

open access: yesGut Microbes, 2023
Maternal immune activation (MIA) derived from late gestational infection such as seen in chorioamnionitis poses a significantly increased risk for neurodevelopmental deficits in the offspring.
Jing Lu   +7 more
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

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