Results 31 to 40 of about 96,711 (304)

ADAR1 restricts LINE-1 retrotransposition [PDF]

, 2016
Adenosine deaminases acting on RNA (ADARs) are involved in RNA editing that converts adenosines to inosines in double-stranded RNAs. ADAR1 was demonstrated to be functional on different viruses exerting either antiviral or proviral effects.
Antonioni, Ambra, Ciafré, Silvia Anna, Doria, Margherita, Frassinelli, Loredana, Galardi, Silvia, Mancone, Carmine, Michienzi, Alessandro, Montaldo, Claudia, Orecchini, Elisa, Tripodi, Marco   +9 more
core   +2 more sources

Research Paper: Experimental Study of the Effect of Stress on the Magnetic Signatures of a Steel Sample [PDF]

فیزیک کاربردی ایران
Before sailing, submarines with ferromagnetic hulls are demagnetized to avoid damage and detection by sea mines and airborne systems. The increase in the residual magnetization of the submarine body after demagnetization due to the rising and falling can
Reza Eslamifar, Mohsen Safikhani, Morteza Mozaffari   +2 more
doaj   +1 more source

Thermosensitive Cationic Magnetic Liposomes for Thermoresponsive Delivery of CPT-11 and SLP2 shRNA in Glioblastoma Treatment

Pharmaceutics, 2023
Thermosensitive cationic magnetic liposomes (TCMLs), prepared from dipalmitoylphosphatidylcholine (DPPC), cholesterol, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)]-2000, and didodecyldimethylammonium bromide (DDAB ...
Yu-Jen Lu, Hao-Lung Hsu, Yu-Hsiang Lan, Jyh-Ping Chen   +3 more
doaj   +1 more source

Genome-wide profiling of uncapped mRNA [PDF]

, 2012
Gene transcripts are under extensive posttranscriptional regulation, including the regulation of their stability. A major route for mRNA degradation produces uncapped mRNAs, which can be generated by decapping enzymes, endonucleases, and small RNAs ...
BD Gregory, C Addo-Quaye, C Llave, JM Franco-Zorrilla, MA German, P Mitchell, R Parker, RA Gutierrez, X Liu, Y Jiao   +9 more
core   +2 more sources

Hyperpolarized δ-[1- 13C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma

Scientific Reports, 2023
TERT promoter mutations are a hallmark of glioblastoma (GBM). Accordingly, TERT and GABPB1, a subunit of the upstream mutant TERT promoter transcription factor GABP, are being considered as promising therapeutic targets in GBM.
Noriaki Minami, Donghyun Hong, Celine Taglang, Georgios Batsios, Anne Marie Gillespie, Pavithra Viswanath, Nicholas Stevers, Carter J. Barger, Joseph F. Costello, Sabrina M. Ronen   +9 more
doaj   +1 more source

GM-CSF Inhibits c-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells. [PDF]

, 2017
Stem cell factor (SCF), the ligand of c-kit, is a key cytokine for hematopoiesis. Hematopoietic precursors express c-kit, whereas differentiated cells of hematopoietic lineage are negative for this receptor, with the exception of NK cells, mast cells ...
Adachi, Alloatti, Ashman, Balan, Banchereau, Bar-On, Barnden, Bonetti, Borg, Breton, Broudy, Broz, Burgdorf, Cavanagh, Cebrian, Di Rosa, Dubois, Eash, Filippi, Gallucci, Guilliams, Haniffa, Heinrich, Helft, Hogquist, Hotchkiss, Huang, Inaba, Kassianos, Kingston, Krishnamoorthy, Lacombe, Lennartsson, Li, Liu, Liu, Lundberg, Lundberg, Lutz, Mensen, Merad, Merad, Mildner, Miller, Nagase, Nair, Oriss, Palucka, Parretta, Pastille, Politikos, Ponzetta, Quinci, Reber, Reith, Ricart, Roskoski, Russell, Saft, Sallusto, Sallusto, Sapoznikov, Sathe, Shortman, Sozzani, Sozzani, Szyska, Testa, van de Laar, von Bonin, Vremec, Wang, Waskow, Welham, Welker, Yang, Yen, Zanoni, Zelenay, Zou   +79 more
core   +2 more sources

The current state of biomarker research for Friedreich's ataxia: a report from the 2018 FARA biomarker meeting [PDF]

, 2019
The 2018 FARA Biomarker Meeting highlighted the current state of development of biomarkers for Friedreich's ataxia. A mass spectroscopy assay to sensitively measure mature frataxin (reduction of which is the root cause of disease) is being developed ...
Blair, Ian A., Farmer, Jennifer, Hersch, Steven, Larkindale, Jane, Lynch, David R., Napierala, Jill, Napierala, Marek, Payne, R. Mark, Subramony, Sub H.   +8 more
core   +1 more source

Candida albicans repetitive elements display epigenetic diversity and plasticity [PDF]

, 2016
Transcriptionally silent heterochromatin is associated with repetitive DNA. It is poorly understood whether and how heterochromatin differs between different organisms and whether its structure can be remodelled in response to environmental signals. Here,
A Ellahi, A Pidoux, A Selmecki, aF Straight, BD Strahl, C Ketel, C Li, C Trapnell, Ca Froyd, CJ Merrick, D Kadosh, DE Gottschling, GD Shankaranarayana, H Chibana, H Chibana, J Haran, J Huang, J Huang, J Nakayama, J Pérez-Martín, J Wendland, JC Tanny, JS Smith, Ka Morano, KR Hansen, L Vasiljeva, LH Freitas-Junior, LN Rusche, M Bryk, M Bühler, M Dubarry, M Paschini, M Van het Hoog, MA Pfaller, MD De Backer, MJ McEachern, N Saksouk, PA Dumesic, PR Lephart, PR Lephart, R Kaur, RB Wilson, RJ Bennett, S Greiss, S Henikoff, S Imai, S Kueng, S Rea, SI Iwaguchi, T Jones, T Kobayashi, T Kobayashi, T Kouzarides, VM Bruno, W Shou, WS Chu, X Bi   +56 more
core   +1 more source

Biomarkers for Huntington's disease: an update [PDF]

, 2012
Huntington's disease (HD) is a devastating autosomal-dominant neurodegenerative condition caused by a CAG repeat expansion in the gene encoding huntingtin which is characterised by progressive motor impairment, cognitive decline and neuropsychiatric ...
Scahill, RI, Tabrizi, SJ, Wild, EJ
core   +1 more source

Genome-wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic variation. [PDF]

, 2013
Spatial relationships within the eukaryotic nucleus are essential for proper nuclear function. In Plasmodium falciparum, the repositioning of chromosomes has been implicated in the regulation of the expression of genes responsible for antigenic variation,
Berriman, Matthew, Eastman, Richard T., Feller, Avi I., Kyes, Sue A., Lemieux, Jacob E., Newbold, Chris I., Otto, Thomas D., Pinches, Robert A., Su, Xin-Zhuan   +8 more
core   +1 more source