Results 11 to 20 of about 29,939 (187)

Magnetic Tweezers in a Microplate Format [PDF]

open access: yesJournal of Visualized Experiments, 2022
Mechanobiology describes how the physical forces and mechanical properties of biological material contribute to physiology and disease. Typically, these approaches are limited single-molecule methods, which restricts their availability. To address this need, a microplate assay was developed that enables mechanical manipulation while performing standard
dos Santos, A., Toseland, C.
openaire   +2 more sources

Twisting and extension: Application of magnetic tweezers to DNA studies

open access: yesAIMS Biophysics, 2023
Magnetic tweezers have emerged as a vital force spectroscopy tool for characterizing the mechanical properties of nucleic acids and their interactions with proteins.
Arsha Moorthy   +3 more
doaj   +1 more source

Magnetic tweezers: development and use in single-molecule research

open access: yesBioTechniques, 2022
The use of magnetic tweezers for single-molecule micromanipulation has evolved rapidly since its introduction approximately 30 years ago. Magnetic tweezers have provided important insights into the dynamic activity of DNA-processing enzymes, as well as ...
Santosh Gaire   +3 more
doaj   +1 more source

Twisted Magnon as a Magnetic Tweezer [PDF]

open access: yesPhysical Review Letters, 2020
6 pages, 4 figures, to appear in ...
Yuanyuan Jiang   +6 more
openaire   +5 more sources

Magnetic tweezers with magnetic flux density feedback control [PDF]

open access: yesReview of Scientific Instruments, 2020
In this work, we present a single-pole magnetic tweezers (MT) device designed for integration with substrate deformation tracking microscopy and/or traction force microscopy experiments intended to explore extracellular matrix rheology and human epidermal keratinocyte mechanobiology.
Waddah I. Moghram   +3 more
openaire   +2 more sources

Scanning a DNA molecule for bound proteins using hybrid magnetic and optical tweezers. [PDF]

open access: yesPLoS ONE, 2013
The functional state of the genome is determined by its interactions with proteins that bind, modify, and move along the DNA. To determine the positions and binding strength of proteins localized on DNA we have developed a combined magnetic and optical ...
Marijn T J van Loenhout   +7 more
doaj   +1 more source

Seconds-scale coherence in a tweezer-array optical clock [PDF]

open access: yes, 2019
Optical clocks based on atoms and ions achieve exceptional precision and accuracy, with applications to relativistic geodesy, tests of relativity, and searches for dark matter.
Eckner, William J.   +5 more
core   +2 more sources

Optical Trapping and Manipulation of Superparamagnetic Beads Using Annular-Shaped Beams

open access: yesMethods and Protocols, 2018
We propose an optical tweezers setup based on an annular-shaped laser beam that is efficient to trap 2.8 μ m-diameter superparamagnetic particles.
Leandro Oliveira   +2 more
doaj   +1 more source

Two energy barriers and a transient intermediate state determine the unfolding and folding dynamics of cold shock protein

open access: yesCommunications Chemistry, 2021
Force-dependent transitions can provide insights into the free-energy landscape of proteins. Here, the authors observe the folding and unfolding dynamics of the model protein Csp using magnetic tweezers, from which a free-energy landscape with two energy
Haiyan Hong   +6 more
doaj   +1 more source

A guide to magnetic tweezers and their applications

open access: yesFrontiers in Physics, 2016
Magnetic force spectroscopy is a rapidly developing single molecule technique that found numerous applications at the interface of physics and biology. Since the invention of the first magnetic tweezers, a number of modifications were incorporated into ...
Rupa Sarkar, Valentin V Rybenkov
doaj   +1 more source

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