Results 41 to 50 of about 1,562,446 (293)

Bioconjugation Strategies for Connecting Proteins to DNA-Linkers for Single-Molecule Force-Based Experiments

open access: yesNanomaterials, 2021
The mechanical properties of proteins can be studied with single molecule force spectroscopy (SMFS) using optical tweezers, atomic force microscopy and magnetic tweezers.
Lyan M. van der Sleen, Katarzyna M. Tych
doaj   +1 more source

Fabrication of nanotweezers and their remote actuation by magnetic fields

open access: yesScientific Reports, 2017
A new kind of nanodevice that acts like tweezers through remote actuation by an external magnetic field is designed. Such device is meant to mechanically grab micrometric objects.
Cécile Iss   +12 more
doaj   +1 more source

Microrheology with optical tweezers: data analysis [PDF]

open access: yes, 2012
We present a data analysis procedure that provides the solution to a long-standing issue in microrheology studies, i.e. the evaluation of the fluids' linear viscoelastic properties from the analysis of a finite set of experimental data, describing (for ...
R M L Evans   +13 more
core   +1 more source

Force measurements with optical tweezers inside living cells [PDF]

open access: yes, 2014
The force exerted by optical tweezers can be measured by tracking the momentum changes of the trapping beam, a method which is more general and powerful than traditional calibration techniques as it is based on first principles, but which has not been ...
Farre, A.   +9 more
core   +1 more source

Phase-sensitive detection in Raman Tweezers: biological applications [PDF]

open access: yes, 2008
In the biomedicine field, scientists act as detectives working hard to unravel the mysteries surrounding cells. To this end, Raman spectroscopy has revealed itself particularly useful, providing information concerning both the chemical composition and ...
De Luca, Anna Chiara
core   +1 more source

Developing a New Biophysical Tool to Combine Magneto-Optical Tweezers with Super-Resolution Fluorescence Microscopy

open access: yesPhotonics, 2015
We present a novel experimental setup in which magnetic and optical tweezers are combined for torque and force transduction onto single filamentous molecules in a transverse configuration to allow simultaneous mechanical measurement and manipulation ...
Zhaokun Zhou   +3 more
doaj   +1 more source

Safety Implications of High-Field MRI: Actuation of Endogenous Magnetic Iron Oxides in the Human Body [PDF]

open access: yes, 2009
Background: Magnetic Resonance Imaging scanners have become ubiquitous in hospitals and high-field systems (greater than 3 Tesla) are becoming increasingly common.
Garcia-Prieto, A   +11 more
core   +1 more source

Characterization of G-Quadruplexes Folding/Unfolding Dynamics and Interactions with Proteins from Single-Molecule Force Spectroscopy

open access: yesBiomolecules, 2021
G-quadruplexes (G4s) are stable secondary nucleic acid structures that play crucial roles in many fundamental biological processes. The folding/unfolding dynamics of G4 structures are associated with the replication and transcription regulation functions
Yuanlei Cheng, Yashuo Zhang, Huijuan You
doaj   +1 more source

Direct observation of chaperone-modulated talin mechanics with single-molecule resolution

open access: yesCommunications Biology, 2022
Chakraborty et al. uses single-molecule magnetic tweezers to investigate the chaperone-modulated talin protein mechanics. The results showed that chaperones are involved in the regulation of talin folding/unfolding under mechanical force with some ...
Soham Chakraborty   +4 more
doaj   +1 more source

Portable magnetic tweezers device enables visualization of the three-dimensional microscale deformation of soft biological materials

open access: yesBioTechniques, 2011
We have designed and built a magnetic tweezers device that enables the application of calibrated stresses to soft materials while simultaneously measuring their microscale deformation using confocal microscopy.
Yali Yang   +4 more
doaj   +1 more source

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