Results 11 to 20 of about 10,587 (256)
Correction-free force calibration for magnetic tweezers experiments [PDF]
Scientific Reports, 2018 Magnetic tweezers are a powerful technique to perform high-throughput and high-resolution force spectroscopy experiments at the single-molecule level. The camera-based detection of magnetic tweezers enables the observation of hundreds of magnetic beads ...
David Dulin, Dulin David
exaly +3 more sources
Magnetic Tweezers in a Microplate Format [PDF]
Journal of Visualized Experiments, 2022 Mechanobiology describes how the physical forces and mechanical properties of biological material contribute to physiology and disease. Typically, these approaches are limited single-molecule methods, which restricts their availability. To address this need, a microplate assay was developed that enables mechanical manipulation while performing standard
dos Santos, A., Toseland, C.
openaire +4 more sources
An Introduction to Magnetic Tweezers
, 2023 AbstractMagnetic tweezers are a single-molecule force and torque spectroscopy technique that enable the mechanical interrogation in vitro of biomolecules, such as nucleic acids and proteins. They use a magnetic field originating from either permanent magnets or electromagnets to attract a magnetic particle, thus stretching the tethering biomolecule ...
Dulin, David
openaire +3 more sources
Quantitative Modeling and Optimization of Magnetic Tweezers [PDF]
Biophysical Journal, 2009 Magnetic tweezers are a powerful tool to manipulate single DNA or RNA molecules and to study nucleic acid-protein interactions in real time. Here, we have modeled the magnetic fields of permanent magnets in magnetic tweezers and computed the forces exerted on superparamagnetic beads from first principles.
Lipfert, Jan +2 more
openaire +3 more sources
Magnetic tweezers to capture the fast-folding λ6-85 in slow motion
Communications PhysicsForce spectroscopy gives access to the underlying free energy landscape of protein folding. Proteins exhibit folding rates between microseconds and hours.
César Augusto Quintana-Cataño +5 more
doaj +2 more sources
Skewed brownian fluctuations in single-molecule magnetic tweezers. [PDF]
PLoS ONE, 2014 Measurements in magnetic tweezers rely upon precise determination of the position of a magnetic microsphere. Fluctuations in the position due to Brownian motion allows calculation of the applied force, enabling deduction of the force-extension response ...
Daniel R Burnham +3 more
doaj +2 more sources
Quadrupole Magnetic Tweezers for Precise Cell Transportation. [PDF]
IEEE Trans Biomed EngThis research introduces a quadrupole magnetic tweezers which can be used for precise cell transportation by actuating magnetic spherical microrobots. The focus of the system is on navigating and manipulating cells within environments characterized by high cellular density. Demonstrating efficacy in moving cells through densely packed cell samples, the
Yang Y, Sokolich M, Mallick S, Das S.
europepmc +3 more sources
Development of electromagnetic tweezers for single-molecule energetics of kinesin [PDF]
Biophysics and PhysicobiologyOptical tweezers have enabled single-molecule measurements of kinesin mechanics and energetics but face challenges for in vivo applications due to photothermal effects and refractive-index-dependent force calibration.
Haruyuki Fukuzawa +7 more
doaj +2 more sources
Measurement of the magnetic moment of single Magnetospirillum gryphiswaldense cells by magnetic tweezers [PDF]
Scientific Reports, 2017 Magnetospirillum gryphiswaldense is a helix-shaped magnetotactic bacterium that synthesizes iron-oxide nanocrystals, which allow navigation along the geomagnetic field.
C. Zahn +9 more
doaj +2 more sources
Twisted Magnon as a Magnetic Tweezer [PDF]
Physical Review Letters, 2020 6 pages, 4 figures, to appear in ...
Yuanyuan Jiang +6 more
openaire +5 more sources