Results 31 to 40 of about 30,016 (261)

Magnetic tweezers for intracellular applications [PDF]

Review of Scientific Instruments, 2003
We have designed and constructed a versatile magnetic tweezer primarily for intracellular investigations. The micromanipulator uses only two coils to simultaneously magnetize to saturation micron-size superparamagnetic particles and generate high magnitude constant field gradients over cellular dimensions. The apparatus resembles a miniaturized Faraday
Hosu, Basarab Gabriel, 1968-, Jakab, Karoly Robert, 1974-, Banki, Peter, Toth, Ferenc I., Forgács, Gabor, 1949-   +4 more
openaire   +1 more source

Portable magnetic tweezers device enables visualization of the three-dimensional microscale deformation of soft biological materials

BioTechniques, 2011
We have designed and built a magnetic tweezers device that enables the application of calibrated stresses to soft materials while simultaneously measuring their microscale deformation using confocal microscopy.
Yali Yang, Jun Lin, Ryan Meschewski, Erin Watson, Megan T. Valentine   +4 more
doaj   +1 more source

Propagation of Bose-Einstein condensates in a magnetic waveguide

, 2002
Gaseous Bose-Einstein condensates of 2-3 million atoms were loaded into a microfabricated magnetic trap using optical tweezers. Subsequently, the condensates were released into a magnetic waveguide and propagated 12 mm.
A. E. Leanhardt, A. P. Chikkatur, B. K. Teo, C. Henkel, D. E. Pritchard, D. Kielpinski, D. Müller, H. Ott, J. D. Weinstein, J. Denschlag, J. Fortagh, J. H. Thywissen, J. Reichel, K. Bongs, M. Key, N. H. Dekker, R. Folman, T. L. Gustavson, T. L. Gustavson, W. Hänsel, W. Ketterle, Y. Shin   +21 more
core   +1 more source

A benchmark data set for the mechanical properties of double-stranded DNA and RNA under torsional constraint

Data in Brief, 2020
Nucleic acids are central to the storage and transmission of genetic information and play essential roles in many cellular processes. Quantitative understanding and modeling of their functions and properties requires quantitative experimental ...
Willem Vanderlinden, Pauline J. Kolbeck, Franziska Kriegel, Philipp U. Walker, Jan Lipfert   +4 more
doaj   +1 more source

Detection of genetic variation and base modifications at base-pair resolution on both DNA and RNA

Communications Biology, 2021
Wang et al. show how genetic sequence and base modifications can be detected simultaneously on single molecules of both DNA and RNA using magnetic tweezers.
Zhen Wang, Jérôme Maluenda, Laurène Giraut, Thibault Vieille, Andréas Lefevre, David Salthouse, Gaël Radou, Rémi Moulinas, Sandra Astete, Pol D’Avezac, Geoff Smith, Charles André, Jean-François Allemand, David Bensimon, Vincent Croquette, Jimmy Ouellet, Gordon Hamilton   +16 more
doaj   +1 more source

Clinical and Experimental Substantiation of the Possibility of Using a 25G Tip to a Permanent Magnet to Remove Intraocular Foreign Bodies

Oftalʹmologiâ, 2022
Purpose: to develop, experimentally study and evaluate in the clinic the effectiveness of using a 25G handpiece to a permanent operating magnet for IOFB removal.Materials and methods.
A. A. Mikhin, S. V. Churashov, A. N. Kulikov, D. S. Ilyushchenkov   +3 more
doaj   +1 more source

Polygonal micro-whirlpools induced in ferrofluids

, 2015
We report on the observation of the polygonal whirlpools in the thin layer of ferrofluid under illumination with a laser beam carrying optical vortex and in the presence of a vertical magnetic field. This kind of structures have attracted attention after
Bacia, Marcin, Drobczynski, Slawomir, Lamperska, Weronika, Marc, Maciej, Masajada, Jan   +4 more
core   +1 more source

Protein-nucleic acids interactions: new ways of connecting structure, dynamics and function [PDF]

, 2017
No abstract ...
Smith, Brian O., Spies, Maria
core   +1 more source

An Introduction to Magnetic Tweezers

, 2023
AbstractMagnetic tweezers are a single-molecule force and torque spectroscopy technique that enable the mechanical interrogation in vitro of biomolecules, such as nucleic acids and proteins. They use a magnetic field originating from either permanent magnets or electromagnets to attract a magnetic particle, thus stretching the tethering biomolecule ...
openaire   +2 more sources

Localized force application reveals mechanically sensitive domains of Piezo1

Nature Communications, 2016
Piezo ion channels transduce mechanical forces into biological signals. Here, the authors use magnetic tweezers to pull specific regions of Piezo1, identifying mechanically sensitive domains that are essential for channel activation and inactivation.
Jason Wu, Raman Goyal, Jörg Grandl
doaj   +1 more source