Results 61 to 70 of about 5,297,615 (283)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Мінеральні ресурси України, 2018 The modern seismic activation of the main oil and gas areas of the Pre-Carpathian foredeep – Dolyna (1974–1976), Nadvirna (1996–2013) and Boryslav (2014–2017) was traced. The refinement of the location of the studied earthquakes courses is carried out on
L. Ye. Nazarevych, A. V. Nazarevych
doaj +1 more source
On the asymptotic magnitude of subsets of Euclidean space
, 2012 Magnitude is a canonical invariant of finite metric spaces which has its origins in category theory; it is analogous to cardinality of finite sets. Here, by approximating certain compact subsets of Euclidean space with finite subsets, the magnitudes of ...
A. Solow +10 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Dedicated comparatives aid comparisons of magnitude: a study with Pitjantjatjara-English bilinguals
Frontiers in Human NeuroscienceWhen expressing comparisons of magnitude, Pitjantjatjara, a language indigenous to the land now known as Australia, employs contextually driven comparators (e.g., Anyupa is tall.
Luke Greenacre +3 more
doaj +1 more source
Magnitude and crystalline anisotropy of hole magnetization in (Ga,Mn)As [PDF]
, 2006 Theory of hole magnetization Mc in zinc-blende diluted ferromagnetic semiconductors is developed relaxing the spherical approximation of earlier approaches. The theory is employed to determine Mc for (Ga,Mn)As over a wide range of hole concentrations and
C. Śliwa +4 more
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Magnitude, diversity, capacities, and dimensions of metric spaces
, 2014 Magnitude is a numerical invariant of metric spaces introduced by Leinster, motivated by considerations from category theory. This paper extends the original definition for finite spaces to compact spaces, in an equivalent but more natural and direct ...
Meckes, Mark W.
core +1 more source
Global metallicity of globular cluster stars from colour-magnitude diagrams [PDF]
, 2002 We have developed an homogeneous evolutionary scenario for H- and He-burning low-mass stars by computing updated stellar models for a wide metallicity and age range (0.0002$\le Z \le$0.004 and 9$\le t(Gyr) \le$15, respectively) suitable to study globular
Alexander +58 more
core +3 more sources