Results 71 to 80 of about 2,455,254 (309)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Dedicated comparatives aid comparisons of magnitude: a study with Pitjantjatjara-English bilinguals

open access: yesFrontiers in Human Neuroscience
When expressing comparisons of magnitude, Pitjantjatjara, a language indigenous to the land now known as Australia, employs contextually driven comparators (e.g., Anyupa is tall.
Luke Greenacre   +3 more
doaj   +1 more source

plasticityai/magnitude: Release 0.0.21

open access: yes, 2018
A fast, efficient universal vector embedding utility ...
Ajay Patel
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

对汶川地震余震序列中最大余震事件的讨论

open access: yesDizhen xuebao, 2018
本文针对2008年5月12日四川汶川MW7.9地震后的余震目录,采用2004年Shcherbakov和Turcotte提出的最大余震震级推断法,给出了最大余震震级的估计值。结果表明,采用现有的余震数据,在大震级区间可能存在一定数量的余震缺失,这造成了余震数据与Gutenberg-Richter定律曲线在大震级区间的差异,导致推断的最大余震震级与使用目录中的最大余震震级存在明显差异。利用震级与断层长度或地表破裂长度之间的经验关系可以看出,由灌县—江油断裂的破裂尺度得到的震级与推断最大余震震级基本一致 ...
Mengyu Xie, Baoping Shi
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

The cause of high intensity of seismicity in Ukraine

open access: yesВісник Київського національного університету імені Тараса Шевченка. Серія Геологія, 2018
In the article, the earthquake near Sumy is considered in detail. According to the authors, this earthquake occurred under the influence of several stress regimes.
O. Chalyi   +7 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

A severe 2017 influenza season dominated by influenza A(H3N2), Victoria, Australia

open access: yesWestern Pacific Surveillance and Response, 2018
Surveillance for influenza-like illness (ILI) and laboratory-confirmed influenza in Victoria, Australia is undertaken jointly by the Victorian Infectious Diseases Reference Laboratory and the Victorian Government Department of Health and Human Services ...
Kristina Grant   +5 more
doaj   +1 more source

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