Results 71 to 80 of about 1,503,596 (264)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
MATHEMATICAL MODEL FOR CALCULATING ENERGY CLASS, INTENSITY AND MAGNITUDE OF THE EARTHQUAKE REAL TIME
Вестник Дагестанского государственного технического университета: Технические науки, 2016 The mathematical dependence, allowing a nomogram based on T.G. Rautian calculates real-time energy class, magnitude and intensity of earthquakes.
G. K. Aslanov +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Frontiers in PediatricsBackgroundNeonatal mortality rate is high in sub-Saharan Africa than high-income countries in relation to the growing wealth disparity. Different factors are linked with neonatal mortality in Ethiopia.
Berhanu Adugna +12 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
GeoHazardsThe Tokara Islands, a volcanic archipelago located south of Japan’s main islands, experienced earthquake swarm activity in 2025. Public concern has emerged regarding the potential triggering of the anticipated Nankai Trough earthquake, which the Japan ...
Tomokazu Konishi
doaj +1 more source
Scaling relation between earthquake magnitude and the departure time from P wave similar growth
Geophysical Research Letters, 2016 We introduce a new scaling relation between earthquake magnitude (M) and a characteristic of initial P wave displacement. By examining Japanese K‐NET data averaged in bins partitioned by Mw and hypocentral distance, we demonstrate that the P wave ...
Shunta Noda, William L. Ellsworth
doaj +1 more source
Геодинамика и тектонофизика, 2015 Studying locations of strong earthquakes (М≥8) in space and time in Central Asia has been among top prob-lems for many years and still remains challenging for international research teams.
S. I. Sherman, Ma Jin, E. A. Gorbunova
doaj +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source