Results 81 to 90 of about 2,113,384 (312)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
The modern seismic activation of the main oil and gas areas of the Pre-Carpathian foredeep – Dolyna (1974–1976), Nadvirna (1996–2013) and Boryslav (2014–2017) was traced. The refinement of the location of the studied earthquakes courses is carried out on
L. Ye. Nazarevych, A. V. Nazarevych
doaj +1 more source
Magnitude-based inferences and absolute changes between initial and final measurements in: Motor imagery group, control group, and between groups (per protocol analysis).
Rado Pisot (448095) +2 more
core +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Dedicated comparatives aid comparisons of magnitude: a study with Pitjantjatjara-English bilinguals
When expressing comparisons of magnitude, Pitjantjatjara, a language indigenous to the land now known as Australia, employs contextually driven comparators (e.g., Anyupa is tall.
Luke Greenacre +3 more
doaj +1 more source
plasticityai/magnitude: Release 0.0.21
A fast, efficient universal vector embedding utility ...
Ajay Patel
core +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Valence and magnitude ambiguity in feedback processing [PDF]
Background: Outcome feedback which indicates behavioral consequences are crucial for reinforcement learning and environmental adaptation. Nevertheless, outcome information in daily life is often totally or partially ambiguous.
Gu, Ruolei +11 more
core +1 more source

