Results 81 to 90 of about 2,455,254 (309)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Seismogeodynamic activation of oil and gas areas of Pre-carpathian foredeep (Dolyna, Nadvirna, Boryslav)

open access: yesМінеральні ресурси України, 2018
The modern seismic activation of the main oil and gas areas of the Pre-Carpathian foredeep – Dolyna (1974–1976), Nadvirna (1996–2013) and Boryslav (2014–2017) was traced. The refinement of the location of the studied earthquakes courses is carried out on
L. Ye. Nazarevych, A. V. Nazarevych
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Magnitude calibration of the seismographic sub-network in NW Saudi Arabia

open access: yes, 2000
Seismic Studies Center, King Saud University, Riyadh, Saudi ArabiaTwo magnitude formulas to be applied in seismic parameter determinations were developed for the seismographic sub-network in NW Saudi Arabia: ML = Log (A / T) + 3.4 Log D + 2.55 and Mc = 2.
Uy, E.A., Punsalan, B.T., Al-Amri, A. M.
core  

Valence and magnitude ambiguity in feedback processing [PDF]

open access: yes, 2017
Background: Outcome feedback which indicates behavioral consequences are crucial for reinforcement learning and environmental adaptation. Nevertheless, outcome information in daily life is often totally or partially ambiguous.
Gu, Ruolei   +11 more
core   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Reinforcer magnitude and demand under fixed-ratio schedules with domestic hens [PDF]

open access: yes, 2014
This study compared three methods of normalizing demand functions to allow comparison of demand for different commodities and examined how varying reinforcer magnitudes affected these analyses.
Grant, Amber A.   +17 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Prevalence of Ear Nose and Throat (ENT) Manifestations Among HIV Seropositive Patients at a Tertiary Hospital in Northern Tanzania: A Descriptive Cross-Sectional Study

open access: yesHIV/AIDS: Research and Palliative Care, 2020
Peter Stephen Shija,1,2 Joshua Alexander Karaba,1,2 Rune Nathaniel Philemon,1,3 Bernard Lucas Minja,1 Philbert Patrick Mtenga,1,2 Denis Robert Katundu1,2 1Kilimanjaro Christian Medical Center Moshi (KCMC), Moshi, Tanzania; 2Department of Ear Nose and ...
Shija PS   +5 more
doaj  

Magnitude-based inference analysis between-groups.

open access: yes, 2016
Trivial area (grey) threshold is -0.2 to 0.2 and bars indicate ±90% confidence limits. AD = absolute decrement; BT = best time; DP = decrement percentage; MT = mean time; RSA1 = RSA test performed before T30; RSA2 = RSA test performed after T30; TT ...
Marcelo Papoti (3387707)   +3 more
core   +1 more source

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