Results 81 to 90 of about 5,297,615 (283)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Seismic effect of industrial explosions of GOK Kostomuksha
Vestnik MGTU, 2020 Active development of quarries in the Republic of Karelia contributes to the improvement of the control system of the parameters of drilling and blasting operations with the aim of ensuring the safety of buildings and structures near mining facilities ...
Zueva I. A., Lebedev A. A.
doaj +1 more source
Sublime in Its Magnitude : The Emancipation Proclamation
, 2007 Book Summary: Lincoln’s reelection in 1864 was a pivotal moment in the history of the United States. The Emancipation Proclamation had officially gone into effect on January 1, 1863, and the proposed Thirteenth Amendment had become a campaign issue ...
Guelzo, Allen C.
core
Sign- and magnitude-tunable coupler for superconducting flux qubits
, 2007 We experimentally confirm the functionality of a coupling element for flux-based superconducting qubits, with a coupling strength $J$ whose sign and magnitude can be tuned {\it in situ}.
A. B. Wilson +20 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The Absolute Magnitude of RRc Variables From Statistical Parallax
, 2012 We present the first definitive measurement of the absolute magnitude of RR Lyrae c-type variable stars (RRc) determined purely from statistical parallax. We use a sample of 247 RRc selected from the All Sky Automated Survey (ASAS) for which high-quality
Albrecht +45 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
HIV/AIDS: Research and Palliative Care, 2020 Peter Stephen Shija,1,2 Joshua Alexander Karaba,1,2 Rune Nathaniel Philemon,1,3 Bernard Lucas Minja,1 Philbert Patrick Mtenga,1,2 Denis Robert Katundu1,2 1Kilimanjaro Christian Medical Center Moshi (KCMC), Moshi, Tanzania; 2Department of Ear Nose and ...
Shija PS +5 more
doaj
Order-of-Magnitude Influence Diagrams [PDF]
, 2011 In this paper, we develop a qualitative theory of influence diagrams that can be used to model and solve sequential decision making tasks when only qualitative (or imprecise) information is available.
Marinescu, Radu, Wilson, Nic
core +1 more source