Results 41 to 50 of about 344,259 (263)

Lubrication Performance of Connecting-Rod and Main Bearing in Different Engine Operating Conditions

open access: yesChinese Journal of Mechanical Engineering, 2019
Only the lubrication performance at rated engine operating condition was generally analyzed in current design and research of engine connecting-rod and main bearing.
Jun Sun   +6 more
doaj   +1 more source

Effects of Bearing Steps on Probable Wear Damage of Main Bearings of an IC Engine

open access: yesInternational Journal of Automotive and Mechanical Engineering, 2021
When two bearing shells are assembled in the bearing housing, it is possible that the edges of the two shells do not fit in the radial direction completely and have an offset relative to each other. This assembly error, which can have different causes, is called the bearing step in this paper. The bearing step can lead to wear damage in bearings.
H. Karimaei, H. R. Chamani
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Gradual Deterioration Behavior of the Load-Bearing Strength of Main Cable Wires in a Suspension Bridge

open access: yesApplied Sciences, 2022
The main cable is the primary load-bearing component of a long-span multi-tower suspension bridge. The interaction between a dead load, vehicle load, wind load, and the corrosion environment leads the main cable wire to exhibit tribo-corrosion-fatigue ...
Hailang Chong   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Investigation of Main Bearing Fatigue Estimate Sensitivity to Synthetic Turbulence Models Using a Novel Drivetrain Model Implemented in OpenFAST

open access: yesWind Energy
A coupled medium‐fidelity drivetrain model is developed and implemented in OpenFAST for a 10‐MW land‐based reference turbine. The implementation is verified against a fully coupled multibody wind turbine model, including a detailed drivetrain.
Veronica Liverud Krathe   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Impact Assessment of Dynamic Loading Induced by the Provision of Frequency Containment Reserve on the Main Bearing Lifetime of a Wind Turbine

open access: yesEnergies, 2023
The components of an operational wind turbine are continuously impacted by both static and dynamic loads. Regular inspections and maintenance are required to keep these components healthy.
Narender Singh   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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