Results 81 to 90 of about 6,305,091 (339)

Forest biodiversity maintenance [PDF]

open access: yes, 2003
The global biodiversity loss within forest ecosystems has attracted attention during the last decades. Awareness increased both world-wide and in Sweden, which led to changes in the Swedish forests policy.
Uliczka, Helen
core  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Maintenance management and servises (case study: PERKESO building's in penisular of Malaysia) [PDF]

open access: yes, 2006
Maintenance Management and Services is a combination of several actions in which to retain or restore an item to perform its required action. PERTUBUHAN KESELAMATAN SOSIAL (PERKESO) as one of the semi government sector in Malaysia that has many assets ...
Hashim, Ahmad Riza
core  

Supporting group maintenance through prognostics-enhanced dynamic dependability prediction [PDF]

open access: yes, 2017
Condition-based maintenance strategies adapt maintenance planning through the integration of online condition monitoring of assets. The accuracy and cost-effectiveness of these strategies can be improved by integrating prognostics predictions and ...
Aizpurua, J. I.   +9 more
core   +1 more source

Sensitivity Analysis of the Coupled Dynamic Behavior of Vehicles in Collision with Semirigid Guardrails

open access: yesShock and Vibration
To quantitatively study the coupled dynamic behavior of vehicles in collision with semirigid guardrails, a coupled numerical model is established based on the finite element method.
Chun Liu   +3 more
doaj   +1 more source

Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis.

open access: yesNew England Journal of Medicine, 2019
BACKGROUND The efficacy of ustekinumab, an antagonist of the p40 subunit of interleukin-12 and interleukin-23, as induction and maintenance therapy in patients with ulcerative colitis is unknown.
B. Sands   +15 more
semanticscholar   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

A Novel State Estimation Approach Based on Adaptive Unscented Kalman Filter for Electric Vehicles

open access: yesIEEE Access, 2020
Accurately estimating the state-of-charge (SOC) of battery is of particular importance for real-time monitoring and safety control in electric vehicles. To obtain better SOC estimation accuracy, a joint modeling method based on adaptive unscented Kalman ...
Jiabo Li   +4 more
doaj   +1 more source

Veliparib with First-Line Chemotherapy and as Maintenance Therapy in Ovarian Cancer.

open access: yesNew England Journal of Medicine, 2019
BACKGROUND Data are limited regarding the use of poly(adenosine diphosphate [ADP]-ribose) polymerase inhibitors, such as veliparib, in combination with chemotherapy followed by maintenance as initial treatment in patients with high-grade serous ovarian ...
R. Coleman   +31 more
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

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