Results 61 to 70 of about 2,403,839 (289)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

OMCTA: A novel knowledge-based technique to evaluate the influence of O&M actions on maintenance management

International Journal of Industrial Engineering and Management, 2020
Human error is a major cause of unavailability of industrial equipment. Consequently, several approaches attempt to assess how this issue influences maintenance management.
C.A. Murad, A.H.A. Melani, M.A.C. Michalski, A.C. Netto, G.F.M. Souza, S.I. Nabeta   +5 more
doaj   +1 more source

Life-cycle of fatigue sensitive structures under uncertainty [PDF]

, 2013
Fatigue is the one of the main contributors to problems related to structural safety of civil and marine structures. Life-cycle management (LCM) techniques considering various uncertainties can be used to predict the safe service life of fatigue ...
Frangopol, Dan M., Soliman, Mohamed
core  

Implementing total productive maintenance in Nigerian manufacturing industries [PDF]

, 2004
Remarkable improvements have occurred recently in the maintenance management of physical assets and productive systems, so that less wastages of energy and resources occur.
Eti, Mark C., Ogaji, S. O. T., Probert, S. D.   +2 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Dynamic Maintenance Cost Optimization in Data Centers: An Availability-Based Approach for K-out-of-N Systems

Buildings
Data Centers (DCs) are critical infrastructures that support the digital world, requiring fast and reliable information transmission for sustainability.
Mostafa Fadaeefath Abadi, Mohammad Javad Bordbari, Fariborz Haghighat, Fuzhan Nasiri   +3 more
doaj   +1 more source

TeamWorker: An agent-based support system for mobile task execution [PDF]

, 2005
Traditional workflow management systems are considered insufficiently flexible to support autonomous job management via close team working. This paper proposes a multi-agent system approach to enhancing existing workflow management systems to enable team-
Lee, H, Mihailescu, P, Shepherdson, J
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Maintenance Knowledge Management with Fusion of CMMS and CM [PDF]

, 2013
- Maintenance can be considered as an information, knowledge processing and management system. The management of knowledge resources in maintenance is a relatively new issue compared to Computerized Maintenance Management Systems (CMMS) and Condition ...
Baglee, David, Björling, Sten-Erik, Galar, Diego, Kumar, Uday, Singh, Sarbjeet   +4 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source