Results 81 to 90 of about 2,403,839 (289)

Integrated reliability centred maintenance approach in public sector facilities management. [PDF]

, 2014
Reliability Centred Maintenance (RCM) is focused on ensuring an asset continues to provide its designed function in its present operating context. Through a number of stages, RCM allows for thorough and constant monitoring of assets to maintain their ...
Bralee, Steve, Marasini, Ramesh
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Dynamic Load Identification on Prefabricated Girder Bridges Based on a CNN and Dynamic Strain Data

Buildings
The vehicle load on a bridge is a critical and dynamic variable. It adversely affects bridges, especially when overloading occurs. Bridges are prone to fatigue damage or collapse.
Lun Zhao, Wenqi Wu, Xuetao Zhang, Liang Li, Pan Guo, Shaolin Yang, Yingchun Cai   +6 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Retracted: Application Based on Artificial Intelligence in Substation Operation and Maintenance Management. [PDF]

Comput Intell Neurosci, 2023
Intelligence And Neuroscience C.
europepmc   +1 more source

Performance management system enhancement and maintenance [PDF]

The research described in this report concludes a two-year effort to develop a Performance Management System (PMS) for the NCC computers. PMS provides semi-automated monthly reports to NASA and contractor management on the status and performance of the ...
Ahour, R., Cleaver, T. G., Johnson, B. R.   +2 more
core   +1 more source

The Temporal Logic of the Tower Chief System [PDF]

, 1990
The purpose is to describe the logic used in the reasoning scheme employed in the Tower Chief system, a runway configuration management system. First, a review of classical logic is given.
Hazelton, Lyman R., Jr.
core   +1 more source

Characterisation of collaborative decision making processes [PDF]

, 2010
This paper deals with the collaborative decision making induced or facilitated by Information and Communication Technologies (ICTs) and their impact on decisional systems. After presenting the problematic, we analyse the collaborative decision making and
Clermont, Philippe, Noyes, Daniel, Seguy, Anne   +2 more
core   +4 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Retracted: Urban Landscaping Landscape Design and Maintenance Management Method Based on Multisource Big Data Fusion. [PDF]

Comput Intell Neurosci, 2023
Intelligence And Neuroscience C.
europepmc   +1 more source