Results 61 to 70 of about 1,388,371 (309)

Multiobjective Optimization for Railway Maintenance Plans [PDF]

Journal of Computing in Civil Engineering, 2018
AbstractRailway track maintenance is a critical problem for any railway administrator. More precisely, preventive maintenance scheduling is a nondeterministic polynomial time (NP)–hard problem, whi...
Daniel Peralta, Christoph Bergmeir, Martin Krone, Marta Galende, Manuel Menéndez, Gregorio Ismael Sainz Palmero, Carlos Martínez Bertrand, Frank Klawonn, José Manuel Benítez 0001   +8 more
openaire   +3 more sources

Maintenance grouping for multi-component systems with availability constraints and limited maintenance teams [PDF]

, 2015
International audienceThe paper deals with a maintenance grouping approach for multi-component systems whose components are connected in series. The considered systems are required to serve a sequence of missions with limited breaks/stoppage durations ...
Barros, Anne, Bérenguer, Christophe, Do Van, Phuc, Vu, Hai Canh   +3 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Monitoring-supported value generation for managing structures and infrastructure systems

Data-Centric Engineering
To maximize its value, the design, development and implementation of structural health monitoring (SHM) should focus on its role in facilitating decision support.
Antonios Kamariotis, Eleni Chatzi, Daniel Straub, Nikolaos Dervilis, Kai Goebel, Aidan J. Hughes, Geert Lombaert, Costas Papadimitriou, Konstantinos G. Papakonstantinou, Matteo Pozzi, Michael Todd, Keith Worden   +11 more
doaj   +1 more source

Modelling Planner-Carrier Interactions in Road Freight Transport: Optimization of Road Maintenance Costs Via Overloading Control

, 2013
A bi-level modelling approach is proposed to represent the interaction between the vehicle loading practices of road freight transport carriers, and the decisions of a road planning authority responsible both for road maintenance and for the enforcement ...
Fowkes, AS, Moreno, E, Watling, DP
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Scheduling unit processing time arc shutdown jobs to maximize network flow over time: complexity results

, 2013
We study the problem of scheduling maintenance on arcs of a capacitated network so as to maximize the total flow from a source node to a sink node over a set of time periods.
Boland, Natashia, Kalinowski, Thomas, Kapoor, Reena, Kaur, Simranjit   +3 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Fuzzy Analytical Hierarchy Process-Based Multi-Criteria Decision Framework for Risk-Informed Maintenance Prioritization of Distribution Transformers

Energies
Effective asset management is crucial for improving the reliability, resilience, and cost efficiency of distribution networks throughout the asset life cycle.
Pannathon Rodkumnerd, Thunpisit Pothinun, Suwilai Phumpho, Neville Watson, Apirat Siritaratiwat, Watcharin Srirattanawichaikul, Sirote Khunkitti   +6 more
doaj   +1 more source

Planning long-term maintenance for electric vehicle charging infrastructure using the Reliability Centered Maintenance (RCM) method [PDF]

, 2012
Electric vehicles (EVs) are mainly known for their advantages as emission free, energy efficient and noiseless transport, but electric mobility has never matured in the automotive market and it remains in the shadow of the internal combustion engine (ICE)
LIOCE, LUIGI
core