Results 81 to 90 of about 3,630,524 (306)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

The principles of planning [1973]

open access: yes, 1973
The Nature of Planning -- Essentials of Planning -- Comprehensive Program of Planning -- Planning Process -- planning ...
Kansas Department of Economic Development, State Planning Division
core  

Development and implementation of preventive-maintenance practices in Nigerian industries. [PDF]

open access: yes, 2006
A methodology for the development of PM using the modern approaches of FMEA, root-cause analysis, and fault-tree analysis is presented. Applying PM leads to a cost reduction in maintenance and less overall energy expenditure.
Probert, Sydney D.   +2 more
core   +1 more source

Combining Reliability-Centered Maintenance with Planning Methodology and Applications in Hard Chrome Plating Plants

open access: yesInternational Journal of Technology, 2015
This article explains the application of the Reliability-Centered Maintenance (RCM) approach to developing maintenance planning in Hard Chrome Plating plants.
B. Suthep, Tadpon Kullawong
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Implementing total productive maintenance in Nigerian manufacturing industries [PDF]

open access: yes, 2004
Remarkable improvements have occurred recently in the maintenance management of physical assets and productive systems, so that less wastages of energy and resources occur.
Probert, Sydney D.   +2 more
core   +1 more source

Preventative maintenance of straddle carriers

open access: yesJournal of Transport and Supply Chain Management, 2015
Background: Robotic vehicles such as straddle carriers represent a popular form of cargo handling amongst container terminal operators. Objectives: The purpose of this industry-driven study is to model preventative maintenance (PM) influences on the ...
Si Li   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Maintenance Planning for Historic Buildings [PDF]

open access: yesBulletin of the Polytechnic Institute of Jassy: Constructions, Architechture Section, 2008
The key to good maintenance of historic buildings is a long-range maintenance plan. Long-range planning recognizes a responsibility to the future to prolong the useful life of a building by preserving it in its present condition and preventing or slowing
Diana Plian, Dan Babor
doaj  

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