Results 81 to 90 of about 3,630,524 (306)
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
The principles of planning [1973]
The Nature of Planning -- Essentials of Planning -- Comprehensive Program of Planning -- Planning Process -- planning ...
Kansas Department of Economic Development, State Planning Division
core
Development and implementation of preventive-maintenance practices in Nigerian industries. [PDF]
A methodology for the development of PM using the modern approaches of FMEA, root-cause analysis, and fault-tree analysis is presented. Applying PM leads to a cost reduction in maintenance and less overall energy expenditure.
Probert, Sydney D. +2 more
core +1 more source
This article explains the application of the Reliability-Centered Maintenance (RCM) approach to developing maintenance planning in Hard Chrome Plating plants.
B. Suthep, Tadpon Kullawong
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Implementing total productive maintenance in Nigerian manufacturing industries [PDF]
Remarkable improvements have occurred recently in the maintenance management of physical assets and productive systems, so that less wastages of energy and resources occur.
Probert, Sydney D. +2 more
core +1 more source
Preventative maintenance of straddle carriers
Background: Robotic vehicles such as straddle carriers represent a popular form of cargo handling amongst container terminal operators. Objectives: The purpose of this industry-driven study is to model preventative maintenance (PM) influences on the ...
Si Li +4 more
doaj +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Maintenance Planning for Historic Buildings [PDF]
The key to good maintenance of historic buildings is a long-range maintenance plan. Long-range planning recognizes a responsibility to the future to prolong the useful life of a building by preserving it in its present condition and preventing or slowing
Diana Plian, Dan Babor
doaj

