Results 71 to 80 of about 210,892 (267)
Abnormal Visual Function: An Under-recognized Risk Factor of Road Traffic Injuries
Journal of Ophthalmic & Vision Research, 2022 Purpose: To determine the relationship between road accidents with visual acuity, refractive errors, visual field, and contrast sensitivity. Methods: This population-based case–control study was conducted on roads leading to Tehran Province, Iran.
Hassan Hashemi +6 more
doaj +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Towards a track maintenance planning tool
, 1998 In Australian rail freight operations, track maintenance costs comprise between 25-35 percent of total train operating costs. The main aim of this paper is to describe the results of research into track maintenance planning for the medium to long-term ...
Simson, Scott +2 more
core
Maintenance Strategies to Reduce Downtime Due to Machine Positional Errors
, 2014 Manufacturing strives to reduce waste and increase Overall Equipment Effectiveness (OEE). When managing machine tool maintenance a manufacturer must apply an appropriate decision technique in order to reveal hidden costs associated with production ...
Longstaff, Andrew P. +5 more
core +1 more source
Diversity Maintenance for Efficient Robot Path Planning
Applied Sciences, 2020 Path planning is present in many areas, such as robotics, video games, and unmanned autonomous vehicles. In the case of robots, it is a primary low-level prerequisite for the successful execution of high-level tasks.
Petar Ćurković, Lovro Čehulić
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Dimensioning windows for railway infrastructure maintenance: Cost efficiency versus traffic impact
, 2016 The Swedish Transport Administration is introducing a new regime, called maintenance windows, for allocating train free slots reserved for maintenance tasks on the railway infrastructure.
Lidén, Tomas +3 more
core +1 more source