Genetic and memetic algorithms for scheduling railway maintenance activities [PDF]
Nowadays railway companies are confronted with high infrastructure maintenance costs. Therefore good strategies are needed to carry out these maintenance activities in a most cost effective way.
Dekker, R., Kaymak, U., Budai-Balke, G.
core
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Fuzzy Risk-Based Maintenance Strategy with Safety Considerations for the Mining Industry. [PDF]
Tubis A +3 more
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Opportunistic Maintenance Strategy for Complex Equipment with a Genetic Algorithm Considering Failure Dependence: A Two-Dimensional Warranty Perspective. [PDF]
Dong E, Gao T, Cheng Z, Wang R, Bai Y.
europepmc +1 more source
National Broadband Strategy 2018-2023 [PDF]
The Government of Kenya presents the National Broadband Strategy (2023) for the country. This strategy builds on the 2013-2017 strategy and takes into account recent technological and industry trends as well as market realities. The vision of NBS 2023 is
core
Maintenance management in Italian manufacturing firms: Matters of size and matters of strategy
Purpose - This paper aims to give a picture of maintenance management in Italian manufacturing firms supported by empirical evidence. The purpose is also to highlight how far maintenance performance and strategies are influenced by context and which ...
CHINESE, Damiana +3 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Organic Farming as an Alternative Maintenance Strategy in the Opinion of Farmers from Natura 2000 Areas. [PDF]
Pawlewicz A +5 more
europepmc +1 more source
Optimising preventive maintenance strategy for production Lines
Preventive Maintenance (PM) is often applied to improve the reliability of production lines. A Split System Approach (SSA) based methodology is presented to assist in making optimal PM decisions for serial production lines.
Mathew, Joseph +5 more
core +1 more source

