Results 121 to 130 of about 5,027,933 (297)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
prepared by the Maintenance Division of the Oregon State Highway Department."March, 1964."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not
core
Prediction cost maintenance model of office building based on condition-based maintenance [PDF]
, 2014 Building maintenance costs are continuously increasing as a result of poor maintenance. Consequently, there is an urgent need to develop solutions to reduce the maintenance costs.
Au-Yong, C.P., Ahmad, F., Ali, A.S.
core +1 more source
Journal of Marine Science and EngineeringThe installation and operation phases are critical stages in the lifecycle of offshore wind turbines, with costs associated with the installation and maintenance of floating wind turbines accounting for approximately 50% of the total investment.
Mingfeng Hu +5 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Research on Reliability Evaluation Method of Metro Signal System
机车电传动, 2018 The reliability of metro signal system is the decisive factor to ensure the safety, availability and maintainability. Aiming at the lack of signal system RAMS evaluation methods, based on vector data model and statistics analysis methods, CBTC interlock ...
MO Zhigang, LUO Hanbin
doaj
Chengshi guidao jiaotong yanjiu［Objective］ The pressure air dryness at the metro vehicle air compressor outlet is a very important indicator. If the water content in the pressure air is high, it will affect the performance of various air-using equipment, and thus affect driving safety.
LI Jianxing, LI Huaizhi
doaj +1 more source
Is telerehabilitation an effective maintenance strategy for patients with chronic obstructive pulmonary diseases: a systematic review. [PDF]
Bull Natl Res Cent, 2023 Uche-Okoye D +8 more
europepmc +1 more source
Analysis of maintenance strategies
, 1998 The most nuclear power utilities have established goals and objectives for their nuclear power plants, including e.g. 1) operating the plant effectively from primarily the safety and secondly the economic point of view, 2) ensuring safety of the public and the plant workers, and 3) providing uninterrupted electric power to the shareholders with long ...
Laakso, Kari, Simola, Kaisa
+5 more sources
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source