Results 131 to 140 of about 332 (158)

ChemInform Abstract: Structure of Maitotoxin

ChemInform, 1993
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. MURATA, H. NAOKI, T. IWASHITA, S. MATSUNAGA, M. SASAKI, A. YOKOYAMA, T. YASUMOTO   +6 more
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Maitotoxin-induced membrane current in neuroblastoma cells

Brain Research, 1987
Maitotoxin (MTX) is a potent marine toxin isolated from the toxic dinoflagellate, Gambierdiscus toxicus. We have examined the possibility of MTX activating calcium channels using cultured neuroblastoma cells (N1E-115). MTX (10 ng/ml) produced a depolarization of the membrane, which was prevented by the removal of Ca2+ from the external medium.
M, Yoshii, A, Tsunoo, Y, Kuroda, C H, Wu, T, Narahashi   +4 more
openaire   +2 more sources

Complete Relative Stereochemistry of Maitotoxin

Journal of the American Chemical Society, 1996
By addressing the relative stereochemistry of the four acyclic portions via organic synthesis, the complete relative stereochemistry of maitotoxin (MTX) has been established as 1B. The relative stereochemistry of the C.1−C.15 portion was elucidated via a two-phase approach:  (1) the synthesis of the eight diastereomers possible for model C ...
Wanjun Zheng, John A. DeMattei, Jiang-Ping Wu, James J.-W. Duan, Laura R. Cook, Hitoshi Oinuma, Yoshito Kishi   +6 more
openaire   +1 more source

Complete structure of maitotoxin

Pure and Applied Chemistry, 1998
Abstract
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Maitotoxin increases inositol phosphates in rat anterior pituitary cells

Journal of Molecular Endocrinology, 1991
ABSTRACT Maitotoxin is a potent marine poison that mobilizes calcium in most vertebrate cell types and accelerates secretion from anterior pituitary cells. It is not known whether voltage-sensitive calcium channels or other mechanisms initiate the effects of maitotoxin on anterior pituitary cells.
SORTINO, Maria Angela, DELAHUNTY, TM, YASUMOTO, T, CRONIN, MJ   +3 more
openaire   +3 more sources

Selective stimulation of Ca2+ flux in cells by maitotoxin

European Journal of Pharmacology: Molecular Pharmacology, 1992
Maitotoxin elicits a dose-dependent stimulation of 45Ca2+ influx in glioma C6, pheochromocytoma PC12, insulinoma HIT and human blood cells, while having no effect in liposomes. In HIT cells maitotoxin also elicited influx of 86Rb+ greater than 22Na+ greater than 54Mn2+, but the stimulation was far less than for 45Ca2+.
M, Murata, F, Gusovsky, T, Yasumoto, J W, Daly   +3 more
openaire   +2 more sources

Modulation of a calcium-activated chloride current by Maitotoxin

Toxicon, 1999
The effect of Maitotoxin (MTX) on the calcium-activated chloride current (ICl-Ca) from Xenopus oocytes was studied, applying the two-electrode voltage clamp technique. MTX increased the current amplitude at all the voltages explored and reduced the time to reach the maximum current level (time to peak). At low toxin concentrations (15 pM), both effects
M, Martínez, C, Salvador, J M, Farias, L, Vaca, L I, Escobar   +4 more
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ChemInform Abstract: Maitotoxin — An Inspiration for Synthesis

ChemInform, 2011
AbstractReview: 220 refs.
K. C. Nicolaou, Robert J. Aversa
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Mechanisms underlying the hemolytic and ichthyotoxic activities of maitotoxin

Natural Toxins, 1999
Maitotoxin (MTX), a putative Ca(2+) channel activator produced by the dinoflagellate Gambierdiscus toxicus showed extremely potent hemolytic and ichthyotoxic activities. Hemolysis of 1% mouse blood cell suspension in saline occurred at 15 nM of MTX.
T, Igarashi, S, Aritake, T, Yasumoto
openaire   +2 more sources

ChemInform Abstract: Complete Structure of Maitotoxin

ChemInform, 1998
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
openaire   +1 more source