Results 51 to 60 of about 332 (158)
Journal of Osteoporosis, Volume 2012, Issue 1, 2012., 2012 P2X7 receptor‐mediated purinergic signaling is a well‐known mechanism involved in bone remodeling. The P2X7 receptor has been implicated in the pathophysiology of various bone and cartilage diseases, including rheumatoid arthritis (RA), a widespread and complex chronic inflammatory disorder. The P2X7 receptor induces the release into the synovial fluid
Alberto Baroja-Mazo +2 more
wiley +1 more source
Maitotoxin, a Ca2+ channel activator candidate.
Journal of Biological Chemistry, 1982 Effects of maitotoxin, the most potent marine toxin, were studied using a rat pheochromocytoma cell line, PC12h. A low concentration (10(-8) g/ml) of maitotoxin induced a profound increase in CA2+ influx into PC12h cells and the Ca2+-dependent release of [3H]norepinephrine from them.
M, Takahashi, Y, Ohizumi, T, Yasumoto
openaire +2 more sources
Synthesis and Biological Evaluation of QRSTUVWXYZA′ Domains of Maitotoxin [PDF]
Journal of the American Chemical Society, 2014 The synthesis of QRSTUVWXYZA' domains 7, 8, and 9 of the highly potent marine neurotoxin maitotoxin (1), the largest secondary metabolite isolated to date, is described. The devised synthetic strategy entailed a cascade Takai-Utimoto ester olefination/ring closing metathesis to construct ring Y, a hydroxydithioketal cyclization/methylation sequence to ...
Nicolaou, K.C. +5 more
openaire +3 more sources
Food Risk Assess Europe, Volume 3, Issue 2, April 2025.Abstract In France, the presence of marine microalgae of the genus Ostreopsis has been identified repeatedly on the Mediterranean coast for several years, whereas on the French Basque coasts its presence is much more recent. In the summers of 2021 and 2022, major Ostreopsis flowering episodes were reported on the Basque coast, resulting in several ...
Rodolphe Lemée +73 more
wiley +1 more source
Role of the Inflammasome, IL‐1β, and IL‐18 in Bacterial Infections
The Scientific World Journal, Volume 11, Issue 1, Page 2037-2050, 2011., 2011 The inflammasome is an important innate immune pathway that regulates at least two host responses protective against infections: (1) secretion of the proinflammatory cytokines IL‐1β and IL‐18 and (2) induction of pyroptosis, a form of cell death. Inflammasomes, of which different types have been identified, are multiprotein complexes containing pattern
Manoranjan Sahoo +4 more
wiley +1 more source
Addressing the safety of new food sources and production systems
Comprehensive Reviews in Food Science and Food Safety, Volume 23, Issue 3, May 2024.Abstract New food sources and production systems (NFPS) are garnering much attention, driven by international trade, changing consumer preferences, potential sustainability benefits, and innovations in climate‐resilient food production systems. However, NFPS can introduce new challenges for food safety agencies and food manufacturers.
Yong Quan Tan +4 more
wiley +1 more source
Detection of Ciguatoxins and Tetrodotoxins in Seafood with Biosensors and Other Smart Bioanalytical Systems [PDF]
, 2023 The emergence of marine toxins such as ciguatoxins (CTXs) and tetrodotoxins (TTXs) in non-endemic regions may pose a serious food safety threat and public health concern if proper control measures are not applied. This article provides an overview of the
Alkassar, Mounira +3 more
core +1 more source
Character evolution of the benthic thecate dinoflagellate, gambierdiscus (Dinophyceae), with an introduction of the interactive key to species [PDF]
, 2015 The genus Gambierdiscus is one of the benthic marine dinoflagellates that are known to produce biotoxins, causing ciguatera food poisoning (CFP) in humans after consuming the contaminated marine fishes. These benthic marine dinoflagellates are commonly
Chui, Pin Leaw +5 more
core +1 more source
Ostreopsis cf. ovata and Ostreopsis lenticularis (Dinophyceae: Gonyaulacales) in the Galapagos Marine Reserve [PDF]
, 2020 The genus of benthic dinoflagellates Ostreopsis is of particular interest because some species negatively impact human health and coastal marine ecosystems.
Andree, Karl B. +6 more
core +1 more source
Development of a quantitative PCR assay for the detection and enumeration of a potentially ciguatoxin-producing dinoflagellate, Gambierdiscus lapillus (Gonyaulacales, Dinophyceae) [PDF]
, 2019 © 2019 Public Library of Science. All rights reserved. Ciguatera fish poisoning (CFP) is an illness contracted through the ingestion of seafood containing ciguatoxins. It is prevalent in tropical regions worldwide, including in Australia. Ciguatoxins are
Kohli, G +3 more
core +1 more source