Results 41 to 50 of about 267 (149)
Role of the Inflammasome, IL‐1β, and IL‐18 in Bacterial Infections
The Scientific World Journal, Volume 11, Issue 1, Page 2037-2050, 2011., 2011 The inflammasome is an important innate immune pathway that regulates at least two host responses protective against infections: (1) secretion of the proinflammatory cytokines IL‐1β and IL‐18 and (2) induction of pyroptosis, a form of cell death. Inflammasomes, of which different types have been identified, are multiprotein complexes containing pattern
Manoranjan Sahoo +4 more
wiley +1 more source
Addressing the safety of new food sources and production systems
Comprehensive Reviews in Food Science and Food Safety, Volume 23, Issue 3, May 2024.Abstract New food sources and production systems (NFPS) are garnering much attention, driven by international trade, changing consumer preferences, potential sustainability benefits, and innovations in climate‐resilient food production systems. However, NFPS can introduce new challenges for food safety agencies and food manufacturers.
Yong Quan Tan +4 more
wiley +1 more source
, 2023 The dinoflagellates Gambierdiscus and Fukuyoa can produce Ciguatoxins (CTXs) and Maitotoxins (MTXs) that lead to ciguatera poisoning (CP). The CP hotspots, however, do not directly relate to the occurrence of the ciguatoxic Gambierdiscus and Fukuyoa ...
Wu, Jiajun +8 more
core +1 more source
The isolation and purification of a caribbean maitotoxin
, 1994 The phenomenon known as red tide has been a topic of great interest in that there is concern that the scale and complexity of this natural phenomenon are expanding. It is known that the benthic dinoflagellate, Gambierdiscus toxicus, produces a variety of polyether toxins that contaminate seafood and result in human illness.
S E Davis, S M Knoepp, B A Lanoue
openaire +2 more sources
Ciguatera: Tropical Reef Fish Poisoning
, 2015 Ciguatera is a neglected seafood-derived illness induced by ciguatoxins, which are derived from toxin precursors (gambiertoxins) produced by the benthic, marine tropical/subtropical dinoflagellates of the genus Gambierdiscus occurring on coral rubble ...
Sparrow, Leanne +3 more
core +1 more source
Inhibition of Maitotoxin‐Induced Ca2+ Influx in Rat Glioma C6 Cells by Brevetoxins and Synthetic Fragments of Maitotoxin [PDF]
Journal of Neurochemistry, 1998 Abstract: 45Ca2+ influx in rat glioma C6 cells induced by 0.3 nM maitotoxin (MTX) was markedly inhibited by brevetoxin A (PbTx1) and brevetoxin B (PbTx2), with EC50 values of 16 and 13 µM, respectively. This inhibition was observed immediately after addition of MTX when monitored with fura‐2, which suggests that PbTx2 directly blocks the action of MTX.
K, Konoki +5 more
openaire +2 more sources
First report of Gambierdiscus in the Western Mediterranean Sea (Balearic Islands) [PDF]
, 2018 Gambierdiscus (Dinophyceae) species are benthic dinoflagellates living in marine littoral zones of circumtropical areas and have recently been described in temperate waters [1].
Rey, Maria +6 more
core
Maitotoxin, a Ca2+ channel activator candidate.
Journal of Biological Chemistry, 1982 Effects of maitotoxin, the most potent marine toxin, were studied using a rat pheochromocytoma cell line, PC12h. A low concentration (10(-8) g/ml) of maitotoxin induced a profound increase in CA2+ influx into PC12h cells and the Ca2+-dependent release of [3H]norepinephrine from them.
M, Takahashi, Y, Ohizumi, T, Yasumoto
openaire +2 more sources
, 2017 © 2016 Phycological Society of America Gambierdiscus is a genus of benthic dinoflagellates found worldwide. Some species produce neurotoxins (maitotoxins and ciguatoxins) that bioaccumulate and cause ciguatera fish poisoning (CFP), a potentially fatal ...
Arjun Verma +9 more
core +1 more source
Characterisation of ciguatoxins
, 2021 The primary objective of this specific grant was to characterize the risk associated to Ciguatera Poisoning (CP) in the EU by developing a sensitive methodology of LC-MS/MS.
Estevez, P. +6 more
core +1 more source