Results 51 to 60 of about 267 (149)

Toxicity of Australian and French-Polynesian Strains of Gambierdiscus-Toxicus (Dinophyceae) Grown in Culture - Characterization of a New Type of Maitotoxin

, 1990
Gambierdiscus toxicus strains isolated from Australia and French Polynesia were grown in modified f2 and f10 nutrient media and the cells extracted for ciguatoxin and maitotoxin.
Lewis, Richard J., Gillespie, Noel C., Lewis, RJ, Gillespie, NC, Holmes, MJ, Holmes, Michael J.   +5 more
core   +1 more source

Sulphated cyclic polyethers produced by toxic Gambierdiscus species

, 2021
The genus Gambierdiscus has been demonstrated to produce a complex array of bioactive, ladder-shaped polyether secondary metabolites, which have varying levels of toxicity.
Michele Prinsep (15402650), Sarah Finch (15395276), Michael Boundy (11615197), Tim Harwood (15394340), Roel van Ginkel (15402956), Sam Murray (11663199), Lesley Rhodes (121240), Jonathan Puddick (187561), Lucy Thompson (3705940)   +8 more
core  

Bimodal Cell Size and Fusing Cells Observed in a Clonal Culture of the Ciguatoxin-Producing Benthic Dinoflagellate Gambierdiscus (WC1/1). [PDF]

Toxins (Basel), 2022
Holmes MJ, Lewis RJ.
europepmc   +1 more source

Sulfo-Gambierones, Two New Analogs of Gambierone Produced by Gambierdiscus excentricus. [PDF]

Mar Drugs, 2021
Yon T, Sibat M, Robert E, Lhaute K, Holland WC, Litaker RW, Bertrand S, Hess P, Réveillon D.   +8 more
europepmc   +1 more source

Folded Conformations of Maitotoxin

, 2008
"We used classical molecular mechanics and dynamicssimulations to sample the conformational space of maitotoxin, thelargest and most lethal natural product. Among the set of minimaobtained, the five conformers with the lowest energies show foldedstructures with an intramolecular hole.
Myrna H. Matus, Marcelo Galván, Laura Escobar   +2 more
openaire   +1 more source

Structural characterisation of 44-Methylgambierone, previously reported as Maitotoxin-3

, 2019
Background Information -- Ciguatera fish poisoning (CFP) is the most common non-microbial food borne illness in the world -- Prevalent in the tropical and sub-tropical waters of the Indo-Pacific Oceans, Caribbean and Mediterranean -- Research activities ...
Michele Prinsep (15402650), Jonathon Puddick (15402647), Sarah Finch (15395276), Tim Harwood (15394340), Frode Rise (292380), Sam Murray (11663199), Alistair Wilkins (15395270), Lesley Rhodes (121240)   +7 more
core  

High abundance of the potentially maitotoxic dinoflagellate Gambierdiscus carpenteri in temperate waters of New South Wales, Australia

, 2014
© 2014 Elsevier B.V. Species of the genus Gambierdiscus are epiphytic dinoflagellates well known from tropical coral reef areas at water temperatures from 24 to 29°C. Gambierdiscus spp.
Harwood, DT, Meyer, L, Capper, A, Rhodes, LL, Hallegraeff, GM, Smith, KF, Kohli, GS, Murray, SA, Neilan, BA, Brett, S   +9 more
core   +2 more sources

Differential Effects of Ciguatoxin and Maitotoxin in Primary Cultures of Cortical Neurons

Chemical Research in Toxicology, 2014
Ciguatoxins (CTXs) and maitotoxins (MTXs) are polyether ladder shaped toxins derived from the dinoflagellate Gambierdiscus toxicus. Despite the fact that MTXs are 3 times larger than CTXs, part of the structure of MTXs resembles that of CTXs. To date, the synthetic ciguatoxin, CTX 3C has been reported to activate voltage-gated sodium channels, whereas ...
Victor Martin, Carmen Vale, Alvaro Antelo, Masahiro Hirama, Shuji Yamashita, Mercedes R. Vieytes, Luis M. Botana   +6 more
openaire   +3 more sources

Toxicity screening of 13 Gambierdiscus strains using neuro-2a and

, 2017
Species in the epi-benthic dinoflagellate genus Gambierdiscus produce ciguatoxins (CTXs) and maitotoxins (MTXs), which are among the most potent marine toxins known.
Adachi, M. (Masao), Amzil, Z. (Zouer), Lam, N. (Nguyen-Ngoc), Séchet, V. (Veronique), Herrenknecht, C. (Christine), Hess, P. (Philipp), Hardison, D.R. (Ramsom), Pisapia, F. (Francesco), Holland, W.C. (William C.), Litaker, R.W. (Wayne), Fraga, S. (Santiago), Nishimura, T. (Tomohiro)   +11 more
core  

Occurrence of three dominant epibenthic dinoflagellates (Ostreopsis spp., Coolia monotis and Prorocentrum lima) in relation to biotic substrates and environmental factors in a highly dynamic ecosystem, the Strait of Gibraltar (Southwestern Mediterranean). [PDF]

Environ Monit Assess, 2022
Ibghi M, El Kbiach ML, Rijal Leblad B, Aboualaalaa H, Hervé F, Sibat M, Chair A, Masseret E, Maamour N, Daoudi M, Amzil Z, Laabir M.   +11 more
europepmc   +1 more source