Results 61 to 70 of about 668,342 (306)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
BMC Plant Biology, 2022 Background Cytoplasmic male sterility (CMS) is a trait of economic importance in the production of hybrid seeds. In CMS-S maize, exerted anthers appear frequently in florets of field-grown female populations where only complete male-sterile plants were ...
Senlin Xiao +7 more
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Change in seed viability of commercial maize hybrids during storage [PDF]
Selekcija i SemenarstvoThe production and processing of commercial seeds place significant emphasis on seed quality, with germination rates being a critical determinant of market performance.
Perić Sanja +5 more
doaj +1 more source
Application of multivariate analysis to electrical penetration graphs using manual and automate waveform recognization from the planthopper Peregrinus maidis feeding on susceptible and resistant maize [PDF]
, 2004 The stylet penetration activities of Peregrinus maidis (Ashmead) (Homoptera: Delphacidae), vector of Maize mosaic virus (MMV) and Maize stripe virus (MStV) were studied by electrical penetration graphs (DC-EPG) on resistant and susceptible maize inbred ...
Buduca, Cécile +5 more
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Transcriptome sequencing analysis of maize embryonic callus during early redifferentiation
BMC Genomics, 2019 Background Maize is one of the primary crops of genetic manipulation, which provides an excellent means of promoting stress resistance and increasing yield.
Xiaoling Zhang +11 more
doaj +1 more source
The AgResults Nigeria Aflasafe TM Challenge Project: 2019 Annual Report [PDF]
, 2020 This report documents the key activities that were carried under the AgResults Aflasafe Pilot Project during the 2018/ 2019 maize-growing season on the verification process to trigger premium payments for successfully harvested and aggregated Aflasafe ...
Akande, A. +7 more
core