Results 51 to 60 of about 364,533 (305)
BMC GenomicsBackground Conserved non-coding sequences (CNS) are islands of non-coding sequences conserved across species and play an important role in regulating the spatiotemporal expression of genes.
Yi Luo +13 more
doaj +1 more source
Weediness and grain yield of specialty maize hybrids cultivated with the application of ecological fertilisers [PDF]
Selekcija i Semenarstvo, 2018 Maize hybrids (Zea mays L.) with specific traits, such as those with red pericarp, high-protein flints or white kernel hybrids, have increased utility value as they contain some vitamins and minerals beneficial to human and animal nutrition. Furthermore,
Simić Milena +5 more
doaj
Evaluation of saline tolerance at the seedling stage of various maize cross combinations
Vietnam Journal of Science, Technology and Engineering, 2017 This study was conducted at the Maize Research Institute of Vietnam using 24 maize hybrids, identified as STM1 to STM24, at five different salt concentrations, which were 0, 50, 100, 150, and 200 mM NaCl.
Huu Hung Nguyen +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Annual progress report 2013: CGIAR Research Program on Maize
, 2014 Annual progress report 2013: CGIAR Research Program on Maize ...
CGIAR Research Program on Maize
core +1 more source
A decade of on-farm data about improved cereal and legume cropping in Mexico
Scientific DataThis data descriptor presents a decade-long agronomic dataset collected between 2012 and 2022 by extension agents across Mexico as part of CIMMYT’s on-farm experimentation network.
Andrea Gardeazábal-Monsalve +12 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source