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Sphingolipids in Major Depression
Neurosignals, 2015 Major depression is one of the most common and severe diseases affecting the world's population. However, the pathogenesis of the disease remains inadequately defined.
Peter L. Jernigan +6 more
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Major depressive disorder [PDF]
Nature Reviews Disease Primers, 2016 Major depressive disorder (MDD) is a debilitating disease that is characterized by depressed mood, diminished interests, impaired cognitive function and vegetative symptoms, such as disturbed sleep or appetite. MDD occurs about twice as often in women than it does in men and affects one in six adults in their lifetime.
Otte, Christian +7 more
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Comprehensive Psychiatry, 2023 Background: To explore the preferences of pediatricians for key factors around the implementation of universal routine screening guidelines for major depressive disorder in adolescent patients in a primary care setting.
Tran T. Doan +4 more
doaj +1 more source
Oxidative Stress and Major Depression [PDF]
Journal of Clinical and Diagnostic Research, 2014 Background: Major causative factor for major depression is inflammation, autoimmune tissue damage and prolonged psychological stress, which leads to oxidative stress.
Ashutosh Bajpai +3 more
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Saffron improved depression and reduced homocysteine level in patients with major depression: A Randomized, double-blind study [PDF]
Avicenna Journal of Phytomedicine, 2017 Objectives: A correlation between hyperhomocysteinemia, and depression has been reported. Saffron (Crocus sativus) is recommended for treatment of depression; hence, in this study the effect of co-administration of saffron and fluoxetine on plasma ...
Gholamali Jelodar +3 more
doaj +1 more source
Frontiers in Psychiatry, 2021 Introduction: An important approach to improve the therapeutic effect of electroconvulsive therapy (ECT) may be to early characterize patients who are more likely to respond.
Louis Simon +8 more
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Nitrous Oxide in Treatment Resistant Major Depression: Should We Laugh About It?
European Psychiatry, 2022 Introduction Nitrous oxide (NO), also known as “laughing gas” is a colorless gas used as an anesthetic, a propellant in some foods, an engine performance enhancer and a recreational drug.
B. Leal +7 more
doaj +1 more source
Venlafaxine for major depression [PDF]
BMJ, 2007 More evidence that risks outweigh benefits for most patients? In this week's BMJ Rubino and colleagues provide new evidence that informs the debate about whether antidepressants increase the risk of suicide.1 The study, a retrospective observational analysis of the General Practice Research Database, found that patients prescribed venlafaxine were ...
Cipriani, A, Geddes, J, Barbui, C
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Cerebellar Contributions to Major Depression
Frontiers in Psychiatry, 2018 Extending beyond the motor domain, the cerebellum is involved in various aspects of cognition and affect. Multidisciplinary evidence has demonstrated topographic organization of higher-order cognitive functions within the cerebellum.
Malte S. Depping +3 more
doaj +1 more source
Major depression disorder - etiology and treatment
Journal of Education, Health and Sport, 2023 Introduction and purpose: The problem of major depression disorder (MDD) affects more and more people. In a few years, it may become the most common disease after cardiovascular diseases and cancer.
Paulina Czuchryta +9 more
doaj +1 more source