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Sphingolipids in Major Depression

open access: yesNeurosignals, 2015
Major depression is one of the most common and severe diseases affecting the world's population. However, the pathogenesis of the disease remains inadequately defined.
Peter L. Jernigan   +6 more
doaj   +4 more sources

Preferences and experiences of pediatricians on implementing national guidelines on universal routine screening of adolescents for major depressive disorder: A qualitative study

open access: yesComprehensive Psychiatry, 2023
Background: To explore the preferences of pediatricians for key factors around the implementation of universal routine screening guidelines for major depressive disorder in adolescent patients in a primary care setting.
Tran T. Doan   +4 more
doaj   +1 more source

Oxidative Stress and Major Depression [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Background: Major causative factor for major depression is inflammation, autoimmune tissue damage and prolonged psychological stress, which leads to oxidative stress.
Ashutosh Bajpai   +3 more
doaj   +1 more source

Saffron improved depression and reduced homocysteine level in patients with major depression: A Randomized, double-blind study [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2017
Objectives: A correlation between hyperhomocysteinemia, and depression has been reported. Saffron (Crocus sativus) is recommended for treatment of depression; hence, in this study the effect of co-administration of saffron and fluoxetine on plasma ...
Gholamali Jelodar   +3 more
doaj   +1 more source

Using EEG to Predict Clinical Response to Electroconvulsive Therapy in Patients With Major Depression: A Comprehensive Review

open access: yesFrontiers in Psychiatry, 2021
Introduction: An important approach to improve the therapeutic effect of electroconvulsive therapy (ECT) may be to early characterize patients who are more likely to respond.
Louis Simon   +8 more
doaj   +1 more source

Nitrous Oxide in Treatment Resistant Major Depression: Should We Laugh About It?

open access: yesEuropean Psychiatry, 2022
Introduction Nitrous oxide (NO), also known as “laughing gas” is a colorless gas used as an anesthetic, a propellant in some foods, an engine performance enhancer and a recreational drug.
B. Leal   +7 more
doaj   +1 more source

Increased insulin resistance due to long COVID is associated with depressive symptoms and partly predicted by the inflammatory response during acute infection [PDF]

open access: yesBrazilian Journal of Psychiatry, 2023
Objective: Some months after the remission of acute COVID-19, some individuals show depressive symptoms, which are predicted by increased peak body temperature (PBT) and decreased blood oxygen saturation (SpO2).
Hussein Kadhem Al-Hakeim   +5 more
doaj   +1 more source

Cerebellar Contributions to Major Depression

open access: yesFrontiers in Psychiatry, 2018
Extending beyond the motor domain, the cerebellum is involved in various aspects of cognition and affect. Multidisciplinary evidence has demonstrated topographic organization of higher-order cognitive functions within the cerebellum.
Malte S. Depping   +3 more
doaj   +1 more source

Major depression disorder - etiology and treatment

open access: yesJournal of Education, Health and Sport, 2023
Introduction and purpose: The problem of major depression disorder (MDD) affects more and more people. In a few years, it may become the most common disease after cardiovascular diseases and cancer.
Paulina Czuchryta   +9 more
doaj   +1 more source

Dealing with major depression in general practice

open access: yesSouth African Family Practice, 2013
One in ten South Africans will be diagnosed with major depressive disorder (MDD) at some point in their lives. MDD is a potentially disabling condition that affects many spheres of an individual’s life and leads to marked social and occupational ...
C.P. Freeman, J.A. Joska
doaj   +1 more source

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