Results 11 to 20 of about 618,469 (262)

Major Depressive Disorder [PDF]

open access: yesNeuron, 2000
In summary, MDD is a highly prevalent major medical whose pathophysiology is still poorly understood. MDD is often recurrent or chronic, and evidence suggests that genetic factors partially influence overall risk of illness but also influence the sensitivity of individuals to the depressogenic effects of environmental adversity.
Fava, Maurizio, Kendler, Kenneth S
openaire   +2 more sources

Immunology of Major Depression [PDF]

open access: yesNeuroimmunomodulation, 2014
High levels of several proinflammatory components of the immune system, such as interleukin-6, C-reactive protein, tumor necrosis factor (TNF)-α, or neopterin in patients suffering from major depression (MD) point to the involvement of an inflammatory process in the pathophysiology of MD. The direct and indirect effects of cytokines on neurotransmitter
openaire   +3 more sources

Increased insulin resistance due to long COVID is associated with depressive symptoms and partly predicted by the inflammatory response during acute infection [PDF]

open access: yesBrazilian Journal of Psychiatry, 2023
Objective: Some months after the remission of acute COVID-19, some individuals show depressive symptoms, which are predicted by increased peak body temperature (PBT) and decreased blood oxygen saturation (SpO2).
Hussein Kadhem Al-Hakeim   +5 more
doaj   +1 more source

Dealing with major depression in general practice

open access: yesSouth African Family Practice, 2013
One in ten South Africans will be diagnosed with major depressive disorder (MDD) at some point in their lives. MDD is a potentially disabling condition that affects many spheres of an individual’s life and leads to marked social and occupational ...
C.P. Freeman, J.A. Joska
doaj   +1 more source

Depression: Special Considerations for the Dental Setting

open access: yesMedEdPORTAL, 2011
The 1-year prevalence rate for depression is 9.5%, or approximately 20.9 million adults in America. The lifetime prevalence of major depressive disorder is approximately 10%-25%.
Jessica G. Hinz
doaj   +1 more source

The interrelation between premenstrual syndrome and major depression: Results from a population-based sample

open access: yesBMC Public Health, 2011
Background Research about the relationship between premenstrual syndrome (PMS) and major depression is limited. This study examined the relationship between moderate to severe PMS and major depression in a population-based sample of women of reproductive
Weiss Carine   +3 more
doaj   +1 more source

Genetics of age-at-onset in major depression

open access: yesTranslational Psychiatry, 2022
Major depression (MD) is a complex, heterogeneous neuropsychiatric disorder. An early age at onset of major depression (AAO-MD) has been associated with more severe illness, psychosis, and suicidality. However, not much is known about what contributes to
Arvid Harder   +5 more
doaj   +1 more source

The Symptom Structure of Postdisaster Major Depression: Convergence of Evidence from 11 Disaster Studies Using Consistent Methods

open access: yesBehavioral Sciences, 2021
Agreement has not been achieved across symptom factor studies of major depressive disorder, and no studies have identified characteristic postdisaster depressive symptom structures. This study examined the symptom structure of major depression across two
Carol S. North, David Baron
doaj   +1 more source

MicroRNAs as a new hope for depression

open access: yesPsychiatry and Behavioral Sciences, 2015
Depression is a common and debilitating illness. Although a great deal of research has been done in the area, its’ neurobiology remains unclear. MicroRNAs are 22 nucleotides long and usually prevent protein synthesis from mRNAs at several stages.
Mehmet Akif Camkurt
doaj   +1 more source

Dealing with major depression in general practice

open access: yesSouth African Family Practice, 2012
One in ten South Africans will be diagnosed with major depressive disorder (MDD) at some point in their lives. MDD is a potentially disabling condition that affects many spheres of an individual’s life and leads to marked social and occupational ...
C.P. Freeman, J.A. Joska
doaj   +1 more source

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