Results 11 to 20 of about 207,642 (302)

Lipidomics in Major Depressive Disorder [PDF]

Frontiers in Psychiatry, 2018
Omic sciences coupled with novel computational approaches such as machine intelligence offer completely new approaches to major depressive disorder (MDD) research.
Andreas Walther, Carlo Vittorio Cannistraci, Carlo Vittorio Cannistraci, Kai Simons, Claudio Durán, Mathias J. Gerl, Susanne Wehrli, Clemens Kirschbaum   +7 more
doaj   +4 more sources

Neurobiology of Major Depressive Disorder [PDF]

Neural Plasticity, 2013
We survey studies which relate abnormal neurogenesis to major depressive disorder. Clinically, descriptive gene and protein expression analysis and genetic and functional studies revised here show that individual alterations of a complex signaling ...
Rosa Villanueva
doaj   +3 more sources

Major Depressive Disorder [PDF]

Neuron, 2000
In summary, MDD is a highly prevalent major medical whose pathophysiology is still poorly understood. MDD is often recurrent or chronic, and evidence suggests that genetic factors partially influence overall risk of illness but also influence the sensitivity of individuals to the depressogenic effects of environmental adversity.
Maurizio Fava, Kenneth S. Kendler
openalex   +4 more sources

Affective Priming in Major Depressive Disorder [PDF]

Frontiers in Integrative Neuroscience, 2012
Research on cognitive biases in depression has provided considerable evidence for the impact of emotion on cognition. Individuals with depression tend to preferentially process mood-congruent material and to show deficits in the processing of positive ...
Joelle eLeMoult, Joelle eLeMoult, K. Lira eYoon, Jutta eJoormann   +3 more
doaj   +3 more sources

Major Depressive Disorder

Harvard Data Science Review, 2018
Flavio Fröhlich
doaj   +4 more sources

Major depressive disorder [PDF]

Nature Reviews Disease Primers, 2016
Major depressive disorder (MDD) is a debilitating disease that is characterized by depressed mood, diminished interests, impaired cognitive function and vegetative symptoms, such as disturbed sleep or appetite. MDD occurs about twice as often in women than it does in men and affects one in six adults in their lifetime.
Stefan M. Gold, Stefan M. Gold, Christian Otte, Alan F. Schatzberg, Amit Etkin, David C. Mohr, Brenda W.J.H. Penninx, Maurizio Fava, Carmine M. Pariante   +8 more
  +11 more sources

Temperament and major depressive disorder [PDF]

Annals of General Psychiatry, 2010
The Lebanese-Arabic TEMPS-A (Temperament Evaluation of the Memphis, Pisa, Paris and San Diego Autoquestionnaire) was used to assess the association between affective temperament and mental disorders in a nationally representative sample of the Lebanese Evaluation of the Burden of Ailments and Needs Of the Nation study(L.E.B.A.N.O.N). The five affective
Mneimneh Zeina, Yeretzian Joumana S, Salamoun Mariana M, Karam Elie G, Karam Aimee N, Fayyad John   +5 more
doaj   +3 more sources

A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression.

PLoS Genetics, 2019
Major depression is a common and severe psychiatric disorder with a highly polygenic genetic architecture. Genome-wide association studies have successfully identified multiple independent genetic loci that harbour variants associated with major ...
Zachary F Gerring, Eric R Gamazon, Eske M Derks, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium   +3 more
doaj   +1 more source

Do Suicide Attempts of Mood Disorder Patients Directly Increase the Risk for a Reattempt?

Frontiers in Psychiatry, 2020
Background: Preceding suicide attempts strongly predict future suicidal acts. However, whether attempting suicide per se increases the risk remains undetermined.
Kari I. Aaltonen, Kari I. Aaltonen, Tom Rosenström, Tom Rosenström, Pekka Jylhä, Pekka Jylhä, Irina Holma, Irina Holma, Mikael Holma, Mikael Holma, Sanna Pallaskorpi, Sanna Pallaskorpi, Kirsi Riihimäki, Kirsi Suominen, Maria Vuorilehto, Maria Vuorilehto, Erkki T. Isometsä, Erkki T. Isometsä   +17 more
doaj   +1 more source

Patient-reported outcomes in major depressive disorder with suicidal ideation: a real-world data analysis using PatientsLikeMe platform

BMC Psychiatry, 2020
Background The current analysis utilized data collected via an online patient community platform, PatientsLikeMe (PLM) to compare patient-reported experiences in patients with major depressive disorder (MDD) with suicidal ideation (MDSI) to those with ...
Stephane Borentain, Abigail I. Nash, Rachna Dayal, Allitia DiBernardo   +3 more
doaj   +1 more source