Results 11 to 20 of about 536,691 (337)

Major Depressive Disorder

Harvard Data Science Review, 2018
Flavio Fröhlich
doaj   +4 more sources

Major depressive disorder [PDF]

Nature Reviews Disease Primers, 2016
Major depressive disorder (MDD) is a debilitating disease that is characterized by depressed mood, diminished interests, impaired cognitive function and vegetative symptoms, such as disturbed sleep or appetite. MDD occurs about twice as often in women than it does in men and affects one in six adults in their lifetime.
Otte, Christian, Gold , Stefan M., Penninx, Brenda W., Pariante, Carmine Maria, Etkin, Amit, Fava, Maurizio, C. Mohr, David, Schatzberg , Alan   +7 more
  +10 more sources

Major Depressive Disorder [PDF]

Neuron, 2000
In summary, MDD is a highly prevalent major medical whose pathophysiology is still poorly understood. MDD is often recurrent or chronic, and evidence suggests that genetic factors partially influence overall risk of illness but also influence the sensitivity of individuals to the depressogenic effects of environmental adversity.
Fava, Maurizio, Kendler, Kenneth S
openaire   +2 more sources

Failure of hippocampal deactivation during loss events in treatment-resistant depression [PDF]

, 2015
Major depressive disorder is characterized by anhedonia, cognitive biases, ruminations, hopelessness and increased anxiety. Blunted responses to rewards have been reported in a number of recent neuroimaging and behavioural studies of major depressive ...
Blair A. Johnston, Cavanagh, David Christmas, J. Douglas Steele, Keith Matthews, Ma, Serenella Tolomeo, Victoria Gradin, Zhang   +8 more
core   +2 more sources

Prevalence and correlates of depressive disorders in people with Type 2 diabetes: results from the International Prevalence and Treatment of Diabetes and Depression (INTERPRET‐DD) study, a collaborative study carried out in 14 countries [PDF]

, 2018
Aims To assess the prevalence and management of depressive disorders in people with Type 2 diabetes in different countries. Methods People with diabetes aged 18–65 years and treated in outpatient settings were recruited in 14 countries and underwent
Ahmed, H. U., Alvarez, A., Bahendeka, S., Basangwa, D., Boborov, A. E., Boden, S., Bulgari, V., Burti, L., Chaturvedi, S. K., Cimino, L. C., de Girolamo, G., Gaebel, W., Gondek, T. M., Guinzbourg de Braude, M., Guntupalli, A., Heinze, M. G., Hong, X., Ji, L., Kamala, T., Khan, A., Kiejna, A., Kokoszka, A., Lalic, N. M., Lecic Tosevski, D., Li, M., Lloyd, C. E., Mankovsky, B., Musau, A., Mussig, K., Ndetei, D., Nouwen, A., Rabbani, G., Sartorius, N., Shevchuk, M., Srikanta, S. S., Starostina, E. G., Taj, R., Vukovic, O., Wolwer, W., Xin, Y.   +39 more
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What patients with bipolar disorder and major depressive disorder perceive as adverse life events precipitating a current major depressive episode

South African Journal of Psychiatry, 2015
Background. Adverse life events (ALEs) as precipitants of a major depressive episode (MDE) have been the subject of many studies. These studies indicate an increase in ALEs in the 6 months preceding an MDE. Objectives.
Robyn Anne van Schoor, Pierre M Joubert
doaj   +1 more source

Comorbid depressive disorders in ADHD. the role of ADHD severity, subtypes and familial psychiatric disorders [PDF]

, 2014
ObjectiveaaTo evaluate the presence of Major Depressive Disorder (MDD) and Dysthymic Disorder (DD) in a sample of Italian children with Attention Deficit Hyperactivity Disorder (ADHD) and to explore specific features of comorbid depressive disorders in ...
Andriola E, Di Roma F, DI TRANI, MICHELA, Donfrancesco R., Leone D, Miano S, PARISI, Pasquale   +6 more
core   +1 more source

Sensor-AssistedWeighted Average Ensemble Model for Detecting Major Depressive Disorder [PDF]

, 2019
The present methods of diagnosing depression are entirely dependent on self-report ratings or clinical interviews. Those traditional methods are subjective, where the individual may or may not be answering genuinely to questions.
Chang, Chuan-Yu, Gao, Liang, Garg, Akhil, Gutiérrez Reina, Daniel, Mahendran, Nivedhitha, Srinivasan, Kathiravan, Vincent, Durai Raj   +6 more
core   +1 more source

A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression.

PLoS Genetics, 2019
Major depression is a common and severe psychiatric disorder with a highly polygenic genetic architecture. Genome-wide association studies have successfully identified multiple independent genetic loci that harbour variants associated with major ...
Zachary F Gerring, Eric R Gamazon, Eske M Derks, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium   +3 more
doaj   +1 more source

Lipidomics in Major Depressive Disorder

Frontiers in Psychiatry, 2018
Omic sciences coupled with novel computational approaches such as machine intelligence offer completely new approaches to major depressive disorder (MDD) research.
Andreas Walther, Carlo Vittorio Cannistraci, Carlo Vittorio Cannistraci, Kai Simons, Claudio Durán, Mathias J. Gerl, Susanne Wehrli, Clemens Kirschbaum   +7 more
doaj   +1 more source