Results 21 to 30 of about 832,143 (393)

Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder

open access: yesJAMA psychiatry, 2020
This randomized clinical trial examines the efficacy of psilocybin as an adjunct to psychotherapy and other treatments for major depressive disorder.
Alan K. Davis   +7 more
semanticscholar   +1 more source

Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures

open access: yesNature Communications, 2021
Major depressive disorder (MDD) has been shown to be associated with structural abnormalities in a variety of spatially diverse brain regions. However, the correlation between brain structural changes in MDD and gene expression is unclear.
Jiao Li   +10 more
semanticscholar   +1 more source

Real-world assessment of treatment inertia in the management of patients treated for major depressive disorder in the USA

open access: yesJournal of Comparative Effectiveness Research, 2023
Aim: Major depressive disorder (MDD) is a debilitating illness in which depressive symptoms may persist after treatment. Treatment inertia is the continued use of the same pharmacotherapy regimen when treatment goals are not met.
John J Sheehan   +6 more
doaj   +1 more source

Ketamine: A New Antidepressant? [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2015
Standart antidepressants are needed for the many individuals with major depressive disorder. However they do not respond adequately to treatment and because of a delay of weeks before the emergence of therapeutic effects.
Feride Karacaer
doaj   +1 more source

Disrupted intrinsic functional brain topology in patients with major depressive disorder

open access: yesMolecular Psychiatry, 2021
Aberrant topological organization of whole-brain networks has been inconsistently reported in studies of patients with major depressive disorder (MDD), reflecting limited sample sizes.
Hong Yang   +72 more
semanticscholar   +1 more source

Suicide‐specific mortality among patients with treatment‐resistant major depressive disorder, major depressive disorder with prior suicidal ideation or suicide attempts, or major depressive disorder alone

open access: yesBrain and Behavior, 2023
Background The impact of treatment‐resistant depression (TRD) or prior suicidal ideation/suicide attempt (SI/SA) on mortality by suicide among patients with major depressive disorder (MDD) is not well known. This retrospective, observational, descriptive
David M. Kern   +7 more
doaj   +1 more source

Brain aging in major depressive disorder

open access: yesEuropean Psychiatry, 2021
Depression and anxiety are common and often comorbid mental health disorders that represent risk factors for aging-related conditions. Brain aging has shown to be more advanced in patients with Major Depressive Disorder (MDD).
L. Han   +7 more
doaj   +1 more source

Major depressive disorder [PDF]

open access: yes, 2007
Depression in its various forms is a commonly seen disorder in general practice. Indeed, over 90% of patients suffering from depression are seen, diagnosed and treated in primal) care.
Bonello, Arlene
core   +1 more source

Major depressive disorder in detention officers

open access: yesRevista de Saúde Pública, 2021
OBJECTIVE To identify factors associated with major depressive disorder (MDD) in detention officers. METHODS This cross-sectional study included all detention officers from the largest prison complex in the state of Bahia, Brazil.
Sheila Nascimento Santos   +3 more
doaj   +2 more sources

Major Depressive Disorder: Advances in Neuroscience Research and Translational Applications

open access: yesNeuroscience Bulletin, 2021
Major depressive disorder (MDD), also referred to as depression, is one of the most common psychiatric disorders with a high economic burden. The etiology of depression is still not clear, but it is generally believed that MDD is a multifactorial disease
Zezhi Li   +3 more
semanticscholar   +1 more source

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