Results 111 to 120 of about 129,386 (217)

Inbreeding does not reduce major histocompatibility complex diversity in the banded mongoose. [PDF]

BMC Ecol Evol
Schubert N, Nichols HJ, Mwanguhya F, Businge R, Kyambulima S, Mwesige K, Cant MA, Winternitz JC.   +7 more
europepmc   +1 more source

Two Decades of Global Research Trends on Major Histocompatibility Complex Class I Gene on Farm Animals: Bibliometric Analysis (2001 to 2020). [PDF]

Vet Med Sci
Maswana M, Malatji DP, Tyasi TL.
europepmc   +1 more source

Antiviral regulator TRIM25 as a prognostic marker of better survival in Merkel cell carcinoma: Association with MCPyV status

International Journal of Cancer, EarlyView.
What's New? TRIM25 is known for its role in antiviral immunity and association with poor prognosis in various cancers. This study reveals an association between high TRIM25 expression and Merkel cell polyomavirus positivity in Merkel cell carcinoma.
Klaus W. Fagerstedt, Sami Kilpinen, Johanna Arola, Benjamin Z. Sundqvist, Tom Böhling, Leif C. Andersson, Harri Sihto   +6 more
wiley   +1 more source

Efficacy and immunogenic effects of Tumor Treating Fields (TTFields) in preclinical models of pancreatic ductal adenocarcinoma, with and without gemcitabine/nab‐paclitaxel

International Journal of Cancer, EarlyView.
What's New? Adaptive immune responses are typically limited in pancreatic ductal adenocarcinoma, resulting in minimal efficacy of immune checkpoint inhibitors. Tumor Treating Fields (TTFields) therapy, which uses low‐intensity intermediate‐frequency electric fields to disrupt cancer cell processes, has been approved for certain cancers.
Tal Kan, Tharwat Haj Khalil, Yiftah Barsheshet, Tali Voloshin, Lilach Koren, Bella Koltun, Cfir David, Kerem Wainer‐Katsir, Avital Vorontsova, Boris Brant, Simona Zisman‐Rozen, Hila M. Ene, Roni Frechtel‐Gerzi, Shay Cahal, Anat Klein‐Goldberg, Lena Lifshitz, Efrat Zemer Tov, Mai Shai, Adi Haber, Moshe Giladi, Uri Weinberg, Yoram Palti   +21 more
wiley   +1 more source

Major Histocompatibility Complex Immunogenetic Diversity Differs Substantially Across Sea Turtle Species and Genomic Regions. [PDF]

Genome Biol Evol
Martin KR, Adkins JL, Chea V, Sarkis CM, Phillips KF, Forsman AM, Seney EE, Komoroske LM, Mansfield KL, Savage AE.   +9 more
europepmc   +1 more source

mRNA Vaccination for Treating Allergy by Modulating Allergen‐Specific Immunity

iLABMED, EarlyView.
This News and Views article discusses the rationale for anti‐allergy vaccine development using a lipid nanoparticle‐mRNA platform. The authors provide additional evidence that supports the potential of using the mRNA approach to combat allergic diseases.
Kun Guo, Lijing Liu, Mingyun Shen, Karin Loré, Ang Lin   +4 more
wiley   +1 more source

Major histocompatibility complex-associated odours [PDF]

Nephrology Dialysis Transplantation, 1998
R, Ferstl, F, Eggert, W, Müller-Ruchholtz   +2 more
openaire   +2 more sources

Construction of a clickable probe‐based protein chip platform for discovering covalent mIDH1 inhibitors from natural medicinal extracts

iMeta, EarlyView.
In this study, we develop a flexible Ccc‐Chip (protein microarray + bioorthogonal click chemistry) for high‐throughput screening of natural covalent active molecules from medicinal plant extracts, identifying flavokawain C from Piper methysticum Forst as a novel covalent mIDH1 inhibitor.
Zhao Cui, Jiameng Li, Caifeng Li, Mo Sun, Wei Liu, Xuxia Cao, Shiwen Deng, Junxian Cao, Hongjun Yang, Peng Chen   +9 more
wiley   +1 more source

Sex-Dependent Influence of Major Histocompatibility Complex Diversity on Fitness in a Social Mammal. [PDF]

Mol Ecol
Schubert N, Nichols HJ, Mwanguhya F, Businge R, Kyambulima S, Mwesige K, Hoffman JI, Cant MA, Winternitz JC.   +8 more
europepmc   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source