Characterization of Major Histocompatibility Complex Genes in Jungle Fowls, Genus Gallus
The Journal of Poultry Science, 2003 Chicken major histocompatibility complex (Mhc) is smaller in size and contains fewer genes than does mammal Mhc. To clarify the characters of Mhc genes in junglefowls as the ancestral species of domestic chickens, we analyzed their Mhc class I B-F and ...
Masahide Nishibori +2 more
doaj +1 more source
SEROLOGICALLY DEFINED AND LYMPHOCYTE-DEFINED COMPONENTS OF THE MAJOR HISTOCOMPATIBILITY COMPLEX IN THE MOUSE [PDF]
, 1972 Fritz H. Bach +3 more
openalex +1 more source
Antiphospholipid Syndrome: An Antibody‐Mediated Disease With Emerging Therapeutic Opportunities
Arthritis &Rheumatology, EarlyView.Antiphospholipid syndrome (APS) is an autoimmune thromboinflammatory disease characterized by vascular thrombosis, pregnancy morbidity, and other manifestations driven by antiphospholipid autoantibodies. In this review, we present a clinical case that illustrates some diagnostic and therapeutic challenges in managing severe, relapsing APS ...
Thalia G. Newman, Jason S. Knight
wiley +1 more source
Gene duplication and fragmentation in the zebra finch major histocompatibility complex
BMC Biology, 2010 Background Due to its high polymorphism and importance for disease resistance, the major histocompatibility complex (MHC) has been an important focus of many vertebrate genome projects. Avian MHC organization is of particular interest because the chicken
Burt David W +10 more
doaj +1 more source
T-lymphocyte response to cytochrome c. I. Demonstration of a T-cell heteroclitic proliferative response and identification of a topographic antigenic determinant on pigeon cytochrome c whose immune recognition requires two complementing major histocompatibility complex-linked immune response genes. [PDF]
, 1979 A M Solinger +3 more
openalex +1 more source
Identification of a CD4+ T cell-stimulating antigen of pathogenic bacteria by expression cloning. [PDF]
, 1995 Identifying the immunogenic proteins that elicit pathogen-specific T cell responses is key to rational vaccine design. While several approaches have succeeded in identifying major histocompatibility complex (MHC) class I bound peptides that stimulate CD8+
Campbell, D +2 more
core +1 more source
Linking Skin and Joint Inflammation in Psoriatic Arthritis through Shared CD8+ T Cell Clones
Arthritis &Rheumatology, EarlyView.Objective Psoriatic arthritis (PsA) is an HLA class I–associated inflammatory arthritis that develops in up to 30% of people with psoriasis. We tested the hypothesis that skin and joint inflammation in PsA is linked in terms of CD8+ T cell phenotype and clonality.
Lucy E. Durham +14 more
wiley +1 more source
Scientific Reports, 2017 The multi-subunit CCR4 (carbon catabolite repressor 4)-NOT (Negative on TATA) complex serves as a central coordinator of all different steps of eukaryotic gene expression.
Alfonso Rodríguez-Gil +9 more
doaj +1 more source
Secretion of mediators following T lymphocyte-macrophage interaction is regulated by the major histocompatibility complex. [PDF]
, 1977 Andrew G. Farr, M E Dorf, Emil R. Unanue
openalex +1 more source
Multiple sclerosis and the major histocompatibility complex
Current Opinion in Neurology, 2009 Multiple sclerosis (MS) is the most common neurological disease affecting young adults. The cause is unknown, but detailed epidemiological and genetic studies have shown a clear inherited component. We review here some of the recent findings of MS genetics with a particular focus on genes of the major histocompatibility complex (MHC).Recent studies add
Ramagopalan, S, Knight, J, Ebers, G
openaire +4 more sources