Results 61 to 70 of about 1,145 (265)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Inequalities on the singular values of an off-diagonal block of a Hermitian matrix
A majorization relating the singular values of an off-diagonal block of a Hermitian matrix and its eigenvalues is obtained. This basic majorization inequality implies various new and existing results.
Li Chi-Kwong, Mathias Roy
doaj
Published as part of Coria, Oscar R., Quiroga, Oscar B., Navarro, José L., Heredia, Javier, Torres, Ricardo & Lima, Javier, 2021, Lista actualizada de las aves de Santiago del Estero, Argentina, pp. 42-143 in Acta Zoológica Lilloana 65 (1) on page 87, DOI: 10.30550/j.azl/2021.65.1/2021-03-16, http://zenodo.org/record ...
Coria, Oscar R. +5 more
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
36. Meganola major major (Hampson, 1891) Nola major Hampson, 1891, Illustrations of Typical Specimens of Lepidoptera Heterocera in the Collection of the British Museum 8: 48. Meganola major (Hampson, 1891): Kononenko and Pinratana, 2013, Moths of Thailand 3 (2): 177 TL: Nilgiri distict, Tamil Nadu, India. Syntypes.
Joshi, Rahul +2 more
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Majorization Problem for q-General Family of Functions with Bounded Radius Rotations
In this paper, we first prove the q-version of Schwarz Pick’s lemma. This result improved the one presented earlier in the literature without proof. Using this novel result, we study the majorization problem for the q-general class of functions with ...
Kanwal Jabeen +3 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

