Results 71 to 80 of about 1,104 (244)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
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, 2000 This article discusses questions in one and several complex variables about the size of the sum of the moduli of the terms of the series expansion of a bounded holomorphic function. Although the article is partly expository, it also includes some previously unpublished results with complete proofs.
openaire +3 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
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Nonlinear Sherman-type inequalities
Advances in Nonlinear Analysis, 2018 An important class of Schur-convex functions is generated by convex functions via the well-known Hardy–Littlewood–Pólya–Karamata inequality. Sherman’s inequality is a natural generalization of the HLPK inequality.
Niezgoda Marek
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Majorization Problem for q-General Family of Functions with Bounded Radius Rotations
MathematicsIn this paper, we first prove the q-version of Schwarz Pick’s lemma. This result improved the one presented earlier in the literature without proof. Using this novel result, we study the majorization problem for the q-general class of functions with ...
Kanwal Jabeen +3 more
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Multidimensional Scaling by Majorization: A Review
Journal of Statistical Software, 2016 A major breakthrough in the visualization of dissimilarities between pairs of objects was the formulation of the least-squares multidimensional scaling (MDS) model as defined by the Stress function.
Patrick J. F. Groenen +1 more
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Matrix majorization via vector majorization
Linear Algebra and its Applications, 2001 The authors study the relation \(SY=X\) between real rectangular matrices \(X,Y\) where \(S\) is a doubly stochastic square matrix. Characterizations are obtained in terms of local action of \(X\) and \(Y\) on vectors, under the assumption of nonnegativity of the product of \((X,e)\) with the Moore-Penrose inverse of \((Y,e)\) where \(e\) is the column
Hwang, Suk-Geun, Pyo, Sung-Soo
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
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